ArticleIndian journal of anaesthesia2018
Paravertebral block with morphine or dexmedetomidine as adjuvant to bupivacaine for post-operative analgesia in modified radical mastectomy: A prospective, randomised, double-blind study.
Article in Indian journal of anaesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Post-operative pain management modalities employed in clinical trials for adult patients in LMIC; a systematic review.BMC anesthesiology · 2021Pooled it
- Pooled it
- Adding Dexmedetomidine to Methylene Blue in Thoracic Paravertebral Block for Video-Assisted Lobectomy: A Case Series Study.Local and regional anesthesia · 2024Article
- Effects of fentanyl and dexmedetomidine as adjuvants to bupivacaine in paravertebral block for postoperative analgesia in patients undergoing modified radical mastectomy: A prospective randomised double-blind study.Indian journal of anaesthesia · 2022Article
- Article
- Comparison of intravenous with perineural dexamethasone for ultrasound-guided erector spinae plane block in patients undergoing modified radical mastectomy-A randomized control trial.Journal of anaesthesiology, clinical pharmacologyArticle
- The efficacy of paravertebral block evaluated by pain-related biomarkers and reactive oxygen species (ROS) following surgery for breast cancer: A randomized controlled study.Saudi journal of anaesthesiaArticle
- Comparison of Morphine and Clonidine as Adjuvants in Paravertebral Block.Anesthesia, essays and researchesArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsGeneral anaesthesia (GA) is the standard technique and paravertebral block (PVB) is suggested as an ideal analgesic in patients undergoing modified radical mastectomy (MRM). This study assessed post-operative analgesic efficacy of morphine or dexmedetomidine as adjuvant to bupivacaine in PVB.
methodsForty-five women (18-60 years) undergoing MRM ± axillary clearance received PVB with 20 ml bupivacaine 0.25% with morphine 3 mg (Group BM) or dexmedetomidine 1 μg/kg (Group BD) in this prospective, randomised, double-blind study. After confirming the onset of PVB, standardised GA induction sequence was used. Intra-operative consumption of fentanyl and propofol along with postoperative morphine and diclofenac consumption, numerical rating scores (NRS) for pain at rest and on movement, nausea and vomiting scores, sedation scores and time to rescue analgesic were recorded. Chi-square or Fisher's exact test and Kruskal-Wallis followed by Mann-Whitney U-test were applied as applicable.
resultsThe number of patients requiring morphine during first 2-h post-operatively was significantly lower (
conclusionMorphine is superior adjuvant to bupivacaine in PVB for modified radical mastectomy than dexmedetomidine.
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