Evidence map›Paper›PMID 29962265›Full record

ArticleAutophagy2018

Induction of a Na

Gang Zhang, Brian T Luk, Morcel Hamidy, Liangfang Zhang, Stephen A Spector

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Autophagy: Regulator of cell death.Cell death & disease · 2023
    Review
  6. The NaFrontiers in endocrinology · 2023
    Review
  7. Autosis as a selective type of cell death.Frontiers in cell and developmental biology · 2023
    Article
  8. Review
  9. Article
  10. Role of NaJournal of molecular medicine (Berlin, Germany) · 2022
    Review
  11. Mitochondria Related Cell Death Modalities and Disease.Frontiers in cell and developmental biology · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Anti-NaScience advances · 2021
    Article
  19. Article
  20. Autosis: A New Target to Prevent Cell Death.JACC. Basic to translational science · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gang Zhanga Division of Infectious Diseases, Department of Pediatrics , University of California San Diego , La Jolla , CA , USA.
Brian T Lukb Department of NanoEngineering and Moores Cancer Center , University of California San Diego , La Jolla , CA , USA.
Morcel Hamidya Division of Infectious Diseases, Department of Pediatrics , University of California San Diego , La Jolla , CA , USA.
Liangfang Zhangb Department of NanoEngineering and Moores Cancer Center , University of California San Diego , La Jolla , CA , USA.
Stephen A Spectora Division of Infectious Diseases, Department of Pediatrics , University of California San Diego , La Jolla , CA , USA.ORCID 0000-0002-1882-4855
University of California San Diego · US

Funding

LOC-IMPAACT Leadership GroupPharmacokinetics and Safety of Remdesivir for Treatment of COVID-19 in Pregnant Women in the USUM1AI068632 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI Sharon A Nachman · 2011 to 2026
$278.1M
Statistical and Data Management Center-Pediatric,Adolescent, and Maternal CTGUM1AI068616 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sean Scott Brummel, Marlene Ann Cooper · 2011 to 2026
$155.6M
LC - IMPAACT Leadership GroupUM1AI106716 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$47.2M
University of California, San Diego Clinical Trial UnitUM1AI069536 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEPHEN A SPECTOR · 2012 to 2026
$34.0M
Nanopeptide Targeting of HIV-CNS Reservoirs without ReactivationR01NS104015 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 2017 to 2021
$2.9M
Modulating Autophagy to Eradicate HIV-1 from CNS ReservoirsR01NS084912 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 2013 to 2017
$1.9M
NIAID NIH HHS UM1 AI068616NIAID NIH HHS UM1 AI068632NIAID NIH HHS UM1 AI069536NIAID NIH HHS UM1 AI106716NINDS NIH HHS R01 NS084912NINDS NIH HHS R01 NS104015
6 · The paper itself

Abstract

Although antiretroviral therapy is highly effective in suppressing human immunodeficiency virus type-1 (HIV) replication, treatment has failed to eliminate viral reservoirs and discontinuation of treatment results in viral reactivation. Here, we demonstrate that peptides Tat-vFLIP-α2 and Tat-Beclin 1/BECN1 which have been shown to induce a Na

Indexed as

AutophagyAntiviral AgentsEnzyme InductionHIV-1HIV InfectionsHumansLipidsMacrophagesModels, BiologicalNanoparticlesPeptidesRNA InterferenceSodium-Potassium-Exchanging ATPaseVirus ReplicationAntiviral AgentsLipidsPeptidesSodium-Potassium-Exchanging ATPaseAutophagic cell deathautophagy-inducing peptideautosischronic HIV infectionHIV preferential killingHIV reservoirTat-Beclin 1Tat-vFLIP

Identifiers

PMID29962265
PMCPMC6103741
OpenAlexW2810401535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.