SynthesisCartilage2020
Articular Cartilage Repair of the Pediatric and Adolescent Knee with Regard to Minimal Clinically Important Difference: A Systematic Review.
Synthesis in Cartilage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Allograft Versus Autograft Osteochondral Transplant for Chondral Defects of the Talus: Systematic Review and Meta-analysis.The American journal of sports medicine · 2022Pooled it
- Management and Outcomes of Osteochondritis Dissecans of the Knee in the Pediatric and Adolescent Population.Current reviews in musculoskeletal medicine · 2026Review
- Medial closing wedge distal femoral varus osteotomy alters the stress distribution pattern of the patellofemoral joint: An evaluation using computed tomography osteoabsorptiometry.Journal of experimental orthopaedics · 2026Article
- Case Report: Arthroscopic synovectomy and loose body removal for charcot knee in an adolescent with congenital insensitivity to pain with anhidrosis.Frontiers in surgery · 2026Article
- Single-Stage Arthroscopically Assisted "Sandwich" Cancellous Bone and Minced Cartilage Implantation for Treatment of Osteochondral Lesions at the Knee Joint.Arthroscopy techniques · 2025Article
- [Patellar cartilage repair-current concepts and evidence].Orthopadie (Heidelberg, Germany) · 2025Review
- Comparison of Clinical, Radiologic, and Arthroscopic Outcomes Between the Microfracture and Microdrilling Techniques for Articular Cartilage Defects in Medial Opening-Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2025Article
- Minced Cartilage Is a One-Step Cartilage Repair Procedure for Small Defects in the Knee-A Systematic-Review and Meta-Analysis.Journal of personalized medicine · 2022Review
- Successful Fixation of Traumatic Articular Cartilage-Only Fragments in the Juvenile and Adolescent Knee: A Case Series.Orthopaedic journal of sports medicine · 2022Article
- Fixation of the Membrane during Matrix-Induced Autologous Chondrocyte Implantation in the Knee: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- AMIC for traumatic focal osteochondral defect of the talar shoulder: a 5 years follow-up prospective cohort study.BMC musculoskeletal disorders · 2021Article
- Reconstruction of Large Osteochondral Lesions in the Knee: Focus on Fixation Techniques.Life (Basel, Switzerland) · 2021Article
- Patterns of Articular Cartilage Thickness in Pediatric and Adolescent Knees: A Magnetic Resonance Imaging-Based Study.Arthroscopy, sports medicine, and rehabilitation · 2021Article
- Anterior Cruciate Ligament Re-tear and Revision Reconstruction in the Skeletally Immature Athlete.Current reviews in musculoskeletal medicine · 2020Review
- Matrix-Augmented Bone Marrow Stimulation With a Polyglycolic Acid Membrane With Hyaluronan vs Microfracture in Local Cartilage Defects of the Femoral Condyles: A Multicenter Randomized Controlled Trial.Orthopaedic journal of sports medicine · 2020Article
- Cartilage Restoration in the Adolescent Knee: a Systematic Review.Current reviews in musculoskeletal medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo perform a systematic review of clinical outcomes following microfracture (MFX), autologous chondrocyte implantation (ACI), osteochondral allograft transplantation (OCA), and osteochondral autograft transplantation system (OATS) to treat articular cartilage lesions in pediatric and adolescent patients. We sought to compare postoperative improvements for each cartilage repair method to minimal clinically important difference (MCID) thresholds.
designMEDLINE, Web of Science, Scopus, and Cochrane Library databases were searched for studies reporting MCID-validated outcome scores in a minimum of 5 patients ≤19 years treated for symptomatic knee chondral lesions with minimum 1-year follow-up. One-sample
resultsTwelve studies reporting clinical outcomes on a total of 330 patients following cartilage repair were identified. The mean age of patients ranged from 13.7 to 16.7 years and the mean follow-up was 2.2 to 9.6 years. Six studies reported on ACI, 4 studies reported on MFX, 2 studies reported on OATS, and 1 study reported on OCA. ACI (
conclusionsOutcomes data on cartilage repair in the pediatric and adolescent knee are limited. This review demonstrates that all available procedures provide postoperative improvement above published MCID thresholds for at least one reported clinical pain or functional outcome score.
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