Evidence map›Paper›PMID 29961843›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Rapid and Extensive Expansion in the United States of a New Multidrug-resistant Escherichia coli Clonal Group, Sequence Type 1193.

Veronika L Tchesnokova, Elena Rechkina, Lydia Larson, Kendra Ferrier, Jamie Lee Weaver, David W Schroeder, Rosemary She, Susan M Butler-Wu, Maria E Aguero-Rosenfeld, Danielle Zerr and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Trends in UropathogenicOpen forum infectious diseases · 2025
    Article
  8. Article
  9. bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. High-riskeLife · 2024
    Article
  16. Gut residentmedRxiv : the preprint server for health sciences · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Veronika L TchesnokovaDepartment of Microbiology, University of Washington School of Medicine, Seattle.
Elena RechkinaID Genomics, Inc, Seattle.
Lydia LarsonDepartment of Microbiology, University of Washington School of Medicine, Seattle.
Kendra FerrierDepartment of Microbiology, University of Washington School of Medicine, Seattle.
Jamie Lee WeaverDepartment of Microbiology, University of Washington School of Medicine, Seattle.
David W SchroederDepartment of Microbiology, University of Washington School of Medicine, Seattle.
Rosemary SheKeck School of Medicine, University of Southern California, Los Angeles.
Susan M Butler-WuKeck School of Medicine, University of Southern California, Los Angeles.
Maria E Aguero-RosenfeldLangone Hospital, New York University.
Danielle ZerrSeattle Children's Hospital.
Ferric C FangDepartment of Microbiology and Harborview Medical Center, University of Washington School of Medicine.
James RalstonKaiser Permanente Washington.
Kim RiddellKaiser Permanente Washington.
Delia ScholesKaiser Permanente Washington.
Scott WeissmanSeattle Children's Hospital.
Kaveri ParkerID Genomics, Inc, Seattle.
Brad SpellbergKeck School of Medicine, University of Southern California, Los Angeles.
James R JohnsonVeterans Affairs Medical Center and University of Minnesota, Minneapolis.
Evgeni V SokurenkoDepartment of Microbiology, University of Washington School of Medicine, Seattle.

Funding

Molecular Clonality of Uropathogenic E. ColiR01AI106007 · NIAID · UNIVERSITY OF WASHINGTON · PI SOKURENKO, EVGENI VENIAMINOVIC · 2014 to 2024
$7.5M
MAb Passive Vaccination against Acinetobacter baumanniiR01AI130060 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRAD J SPELLBERG · 2017 to 2026
$6.7M
Clonotyping Technology for Prediction of Antibiotic ResistanceR42AI116114 · NIAID · IDGENOMICS, INC. · PI SOKURENKO, EVGENI VENIAMINOVIC, ZUCKERMAN, LINDA · 2016 to 2018
$3.0M
Transferrin Combination Therapy to Address Antimicrobial ResistanceR01AI117211 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SPELLBERG, BRAD J · 2016 to 2019
$2.7M
Clonotyping Technology for Prediction of Antibiotic ResistanceR41AI116114 · NIAID · IDGENOMICS, INC. · PI APRIKIAN, PAVEL, SOKURENKO, EVGENI VENIAMINOVIC · 2015 to 2015
$214k
CSRD VA I01 CX000192NIAID NIH HHS R01 AI106007NIAID NIH HHS R01 AI117211NIAID NIH HHS R01 AI130060NIAID NIH HHS R41 AI116114NIAID NIH HHS R42 AI116114
6 · The paper itself

Abstract

We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone-sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates.

Indexed as

Drug Resistance, Multiple, BacterialCommunicable Diseases, EmergingEscherichia coliEscherichia coli InfectionsHumansPopulation SurveillancePrevalenceRetrospective StudiesUnited States

Identifiers

PMID29961843
PMCPMC6321845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.