Evidence map›Paper›PMID 29961683›Full record

ArticleThe Journal of rheumatology2018

Hospitalization Increases the Risk of Acute Arthritic Flares in Gout: A Population-based Study over 2 Decades.

Nour Zleik, Mohanad M Elfishawi, Zoran Kvrgic, Clement J Michet, Cynthia S Crowson, Eric L Matteson, Tim Bongartz

Open access · greenAbstract read
In one paragraph

Article in The Journal of rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. [Gout : From the diagnosis to guideline-based treatment].Zeitschrift fur Gerontologie und Geriatrie · 2025
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Acute arthritis following SARS-CoV-2 infection.Journal of medical virology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nour ZleikFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Mohanad M ElfishawiFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Zoran KvrgicFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Clement J MichetFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Cynthia S CrowsonFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA. crowson@mayo.edu.
Eric L MattesonFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Tim BongartzFrom the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NCATS NIH HHS UL1 TR000135NCATS NIH HHS UL1 TR002377NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

objectiveTo assess in-hospital gout flares in patients with gout.

methodsHospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010.

resultsThere were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001).

conclusionHospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.

Indexed as

HospitalizationAdultAgedCohort StudiesFemaleGoutHumansHyperuricemiaLongitudinal StudiesMaleMiddle AgedRisk FactorsUnited StatesGOUTHEALTHCARE USEHOSPITALIZATIONHYPERURICEMIA

Identifiers

PMID29961683
PMCPMC6072557
OpenAlexW2810567334

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.