ArticleThe Journal of thoracic and cardiovascular surgery2018
An in vitro evaluation of turbulence after transcatheter aortic valve implantation.
Article in The Journal of thoracic and cardiovascular surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Development and preclinical results of a transcatheter aortic valve implant with novel polymeric leaflets.NPJ cardiovascular health · 2026Article
- Optimizing Aortic Valve Replacement Through Strategic Upsizing: A Modern Framework for Lifetime Valve Management.Diseases (Basel, Switzerland) · 2026Review
- In Vitro Hydrodynamic Evaluation of Pulmonary Expanded Polytetrafluoroethylene Valved Conduits.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Novel Technique Employing Transcatheter Balloon-Expandable Valves in Pure Aortic Regurgitation: A Proof-of-Concept Study.Structural heart : the journal of the Heart Team · 2025Article
- Redo-Transcatheter Aortic Valve Replacement Procedural Optimization and Patient Selection: From Bench to Clinical Practice.Journal of clinical medicine · 2025Review
- Assessing the Impact of Cardiac Output and Valve Orientation on Bioprosthetic Pulmonary Valve Hemodynamics Using In Vitro 4D-Flow MRI and High-Speed Imaging.Cardiovascular engineering and technology · 2025Article
- Recommendations for defining disturbed flow as laminar, transitional, or turbulent in assays of hemostasis and thrombosis: communication from the ISTH SSC Subcommittee on Biorheology.Journal of thrombosis and haemostasis : JTH · 2025Review
- Analysis of Energy and Pressure in the Sinus with Different Blood Pressures after Bioprosthetic Aortic Valve Replacement.Annals of biomedical engineering · 2024Article
- Large Field-of-View Intravascular Ultrasound for Mitral and Tricuspid Valve-in-Valve Guidance: A Pilot Study.Structural heart : the journal of the Heart Team · 2024Article
- Effect of Blood Pressure Levels on Sinus Hemodynamics in Relation to Calcification After Bioprosthetic Aortic Valve Replacement.Annals of biomedical engineering · 2024Article
- Differential Impact of Blood Pressure Control Targets on Epicardial Coronary Flow After Transcatheter Aortic Valve Replacement.Structural heart : the journal of the Heart Team · 2024Article
- Comparison of self- and balloon-expandable valves in patients with dilatated ascending aorta undergoing transcatheter aortic valve replacement.Journal of thoracic disease · 2023Article
- An In-Vitro Study of the Flow Past a Transcatheter Aortic Valve Using Time-Resolved 3D Particle Tracking.Annals of biomedical engineering · 2023Article
- The Influence of Aortic Valve Disease on Coronary Hemodynamics: A Computational Model-Based Study.Bioengineering (Basel, Switzerland) · 2023Article
- The Accelerated Transcatheter Heart Valve Testing Environment: Loading, Motion, and Fluid Dynamics.Journal of biomechanical engineering · 2023Article
- Changes in platelet function and coagulation after transcatheter aortic valve implantation evaluated with thromboelastography.Open heart · 2022Observational
- Biomechanics of Transcatheter Aortic Valve Implant.Bioengineering (Basel, Switzerland) · 2022Review
- Comparison of performance of self-expanding and balloon-expandable transcatheter aortic valves.JTCVS open · 2022Article
- Effects of MitraClip Therapy on Mitral Flow Patterns and Vortex Formation: An In Vitro Study.Annals of biomedical engineering · 2022Article
- How to deal with low-flow low-gradient aortic stenosis and reduced left ventricle ejection fraction: from literature review to tips for clinical practice.Heart failure reviews · 2022Review
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6 authors.
Funding
Abstract
backgroundThis study aimed at assessment of post-transcatheter aortic valve (TAV) replacement hemodynamics and turbulence when a same-size SAPIEN 3 (Edwards Lifesciences Corp, Irvine, Calif) and Medtronic Evolut (Minneapolis, Minn) were implanted in a rigid aortic root with physiological dimensions and in a representative root with calcific leaflets obtained from patient computed tomography scans.
methodsTAV hemodynamics were studied by placing a SAPIEN 3 26-mm and an Evolut 26-mm in rigid aortic roots and representative root with calcific leaflets under physiological conditions. Hemodynamics were assessed using high-fidelity particle image velocimetry and high-speed imaging. Transvalvular pressure gradients (PGs), pinwheeling indices, and Reynolds shear stress (RSS) were calculated.
results(1) PGs obtained with the Evolut and the SAPIEN 3 were comparable among the different models (10.5 ± 0.15 mm Hg vs 7.76 ± 0.083 mm Hg in the rigid model along with 13.9 ± 0.19 mm Hg vs 5.0 ± 0.09 mm Hg in representative root with calcific leaflets obtained from patient computed tomography scans respectively); (2) more pinwheeling was found in the SAPIEN 3 than the Evolut (0.231 ± 0.057 vs 0.201 ± 0.05 in the representative root with calcific leaflets and 0.366 ± 0.067 vs 0.122 ± 0.045 in the rigid model); (3) higher rates of RSS were found in the Evolut (161.27 ± 3.45 vs 122.84 ± 1.76 Pa in representative root with calcific leaflets and 337.22 ± 7.05 vs 157.91 ± 1.80 Pa in rigid models). More lateral fluctuations were found in representative root with calcific leaflets.
conclusions(1) Comparable PGs were found among the TAVs in different models; (2) pinwheeling indices were found to be different between both TAVs; (3) turbulence patterns among both TAVs translated according to RSS were different. Rigid aortic models yield more conservative estimates of turbulence; (4) both TAVs exhibit peak maximal RSS that exceeds platelet activation 100 Pa threshold limit.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.