Evidence map›Paper›PMID 29961356›Full record

ArticleAIDS care2018

Exploring the dynamics of ART adherence in the context of a mindfulness instruction intervention among youth living with HIV in Baltimore, Maryland.

Deanna Kerrigan, Suzanne M Grieb, Jonathan Ellen, Erica Sibinga

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deanna Kerrigana Department of Health, Behavior & Society , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Suzanne M Griebb Department of Pediatrics , Johns Hopkins School of Medicine , Baltimore , MD , USA.
Jonathan Ellenc Johns Hopkins All Children's Hospital , St. Petersburg , FL , USA.
Erica Sibingab Department of Pediatrics , Johns Hopkins School of Medicine , Baltimore , MD , USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Improving Treatment Adherence in HIV-Positive Youth Through Mindfulness TrainingR01AT007888 · NCCIH · JOHNS HOPKINS UNIVERSITY · PI SIBINGA, ERICA · 2013 to 2017
$2.2M
NCCIH NIH HHS R01 AT007888NIAID NIH HHS P30 AI094189
6 · The paper itself

Abstract

Youth living with HIV have sub-optimal rates of adherence to antiretroviral therapy (ART). Mindfulness instruction interventions have shown promise for improving medication adherence, but the effects and mechanisms of these interventions are still being explored among people living with HIV, including youth. In the context of a randomized controlled trial of the efficacy of a Mindfulness-Based Stress Reduction (MBSR) program on ART adherence and viral suppression among youth living with HIV, we conducted 44 iterative, semi-structured, in-depth interviews with 20 study participants (13-24 years) recruited from clinics at two academic centers in Baltimore, Maryland. Interviews explored the social context and psychosocial dynamics of ART adherence in the context of the MBSR intervention, compared with those in a control arm. We employed thematic content analysis to systematically code and synthesize textual interview data. Participants' challenges with ART adherence were often situated within an ongoing process of working to manage HIV as a stigmatized, chronic condition in addition to other intersecting social stigmas, inequalities, and stressors. Participation in the MBSR program and related group support allowed participants to non-judgmentally observe and accept difficult thoughts, feelings, and experiences associated with living with HIV and taking ART, which facilitated greater reported adherence. Mindfulness training may stimulate new perspectives and understanding, including greater self- and illness-acceptance among youth living with HIV, leading to improved HIV outcomes.

Indexed as

MindfulnessAdolescentAnti-HIV AgentsBaltimoreFemaleHIV InfectionsHumansMaleMedication AdherenceSocial EnvironmentSocial StigmaYoung AdultAnti-HIV AgentsadherenceHIVmindfulnessstigmayouth

Identifiers

PMID29961356
PMCPMC6793430

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.