Evidence map›Paper›PMID 29961244›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2018

Turkish Insulin Injection Techniques Study: Complications of Injecting Insulin Among Turkish Patients with Diabetes, Education They Received, and the Role of Health Care Professional as Assessed by Survey Questionnaire.

Selcuk Dagdelen, Oguzhan Deyneli, Nermin Olgun, Zeynep Osar Siva, Mehmet Sargin, Sükrü Hatun, Mustafa Kulaksizoglu, Ahmet Kaya, Cansu Aslan Gürlek, Laurence J Hirsch and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Insulin Injection Technique is Associated with Glycemic Variability in Patients with Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2018
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Selcuk DagdelenDepartment of Endocrinology and Metabolism, Hacettepe University School of Medicine, Hacettepe Mah., 06230, Sıhhıye, Ankara, Turkey.
Oguzhan DeyneliDepartment of Endocrinology and Metabolism, Koc University School of Medicine, Davutpasa Cad. No: 4, 34010, Topkapı, Istanbul, Turkey.
Nermin OlgunNursing Department, Faculty of Health Sciences, Hasan Kalyoncu University, Havaalanı Yolu Üzeri 8. km, Sahinbey, Gaziantep, Turkey.
Zeynep Osar SivaDepartment of Endocrinology, Diabetes and Metabolism, Cerrahpasa School of Medicine, Istanbul University, Cerrahpasa Mah. Kocamustafapasa Cad. No: 53, 34098, Fatih, Istanbul, Turkey.
Mehmet SarginFaculty of Medicine, Istanbul Medeniyet University, Egitim Mah. Dr. Erkin Cad., 34722, Kadıköy, Istanbul, Turkey.
Sükrü HatunDepartment of Pediatric Endocrinology and Diabetes, Koc University School of Medicine, Davutpasa Cad. No: 4, 34010, Topkapı, Istanbul, Turkey.
Mustafa KulaksizogluDepartment of Endocrinology and Metabolism, Meram Faculty of Medicine, Necmettin Erbakan University, Yunus Emre Mah. Beysehir Cad. No: 281, 42080, Meram, Konya, Turkey.
Ahmet KayaDepartment of Endocrinology and Metabolism, Meram Faculty of Medicine, Necmettin Erbakan University, Yunus Emre Mah. Beysehir Cad. No: 281, 42080, Meram, Konya, Turkey.
Cansu Aslan GürlekBD Diabetes Care, Ruzgarlibahce Mah. S.Sinan Eroglu Cad. No: 6, Akel Is Merkezi A Blok -3. Kat, Kavacik, 34805, Beykoz, Istanbul, Turkey.
Laurence J HirschBD Diabetes Care, Franklin Lakes, NJ, USA.
Kenneth W StraussBD Diabetes Care, POB 13, Erembodegem-Dorp 86, 9320, Erembodegem, Belgium. kenneth.strauss@bd.com.ORCID http://orcid.org/0000-0002-1031-0067
ITQ Turkish Study Group
Koç University · TRNecmettin Erbakan University · TRDiabetes Care Center · USHacettepe University · TRHasan Kalyoncu University · TRIstanbul Medeniyet University · TRIstanbul University-Cerrahpaşa · TROrdem dos Médicos · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUsing the Turkish and rest of world (ROW) Injection Technique Questionnaire (ITQ) data we address key insulin injection complications.

methodsSummarized in first ITQ paper.

resultsNearly one-third of Turkish insulin users described lesions consistent with lipohypertrophy (LH) at their injection sites and 27.4% were found to have LH by the examining nurse (using visual inspection and palpation). LH lesions in the abdomen and thigh of Turkish patients are slightly smaller than those measured in ROW but more than half of Turkish patients who have LH continue to inject into them at least daily. More than a quarter of Turkish patients have frequent unexplained hypoglycemia and nearly 2 out of 5 have glycemic variability, both of which have been linked to the presence of LH and the habit of injecting into it. Nearly half of Turkish injectors report having pain on injection. Of these, just over half report having painful injections only several times a month or year (i.e., not with every injection). In Turkey the diabetes nurse has by far the major role in teaching patients how to inject. Nearly 40% of Turkish injectors get their sites checked at least annually, and a larger proportion than ROW had received recent (within the last 12 months) instruction on how to inject properly.

conclusionTurkish patients and professionals have clearly made progress in injection technique, but there are still considerable challenges ahead which the new Turkish guidelines will help address.

fundingBD Diabetes Care.

Indexed as

InfusionsInjectionsInsulinLipodystrophyLipohypertrophyNeedlesNeedlestickSubcutaneous

Identifiers

PMID29961244
PMCPMC6064601
OpenAlexW2810150078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.