Evidence map›Paper›PMID 29961232›Full record

ArticleNeurochemical research2018

Neohesperidin Prevents Aβ

Jijun Wang, Yingchun Yuan, Peng Zhang, Huixian Zhang, Xiaomei Liu, Yuelin Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

  1. assessment of antioxidant, neuroprotective, anti-urease and anti-tyrosinase capacities of leaves extracts.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jijun WangDepartment of Medicine, Xi'an Jiaotong University, No. 76 Yanta West Road, Yanta District, Xi'an, 710061, China.
Yingchun YuanShaanxi Province People's Hospital, No. 256 Youyi West Road, Yanta District, Xi'an, 710068, China.
Peng ZhangShaanxi Province People's Hospital, No. 256 Youyi West Road, Yanta District, Xi'an, 710068, China.
Huixian ZhangShaanxi Province People's Hospital, No. 256 Youyi West Road, Yanta District, Xi'an, 710068, China.
Xiaomei LiuShaanxi Province People's Hospital, No. 256 Youyi West Road, Yanta District, Xi'an, 710068, China.
Yuelin ZhangDepartment of Medicine, Xi'an Jiaotong University, No. 76 Yanta West Road, Yanta District, Xi'an, 710061, China. zhangylzhyl@126.com.ORCID http://orcid.org/0000-0003-2987-8645
Shanxi Medical University · CN

Funding

Shaanxi Province Natural Science Foundation of China S2015YFJM2252
6 · The paper itself

Abstract

A growing body of literature has established a link between the cerebral ischaemic injury and pathological state of Alzheimer's disease (AD), and this correlation indicated that the preventive agent for ischaemia might improve the pathology of AD. Our previous studies have demonstrated that Neohesperidin (NH) exhibited neuroprotective effects against cerebral ischemia via the down-regulation of Bcl-2, Akt/PI3K and Nrf2 pathways. In the present study, we first confirmed the protective effects of NH on Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsApoptosisBrain IschemiaHesperidinHippocampusNeuronsNeuroprotective AgentsPeptide FragmentsProtein Disulfide-IsomerasesRats, Sprague-DawleyAmyloid beta-Peptidesamyloid beta-protein (25-35)HesperidinneohesperidinNeuroprotective AgentsPeptide FragmentsProtein Disulfide-IsomerasesAβ25–35ER stressNeohesperidinPDIS-Nitrosylation

Identifiers

PMID29961232
OpenAlexW2810534098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.