ArticleOdontology2019
Teeth whitening with 6% hydrogen peroxide and its impact on quality of life: 2 years of follow-up.
Article in Odontology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02353611 (Safety and Efficacy of a Light-activated 6% Hydrogen Peroxide With Nitrogen-doped Titanium Dioxide Tooth Bleaching Agent), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of a Light-activated 6% Hydrogen Peroxide With Nitrogen-doped Titanium Dioxide Tooth Bleaching Agent
Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- Clinical comparison of whitening efficacy and tooth sensitivity of different concentrations of hydrogen peroxide photoactivated with violet or blue LEDs.Lasers in medical science · 2024Trial
- In-office dental bleaching in adolescents using 6% hydrogen peroxide with and without gingival barrier: a randomized double-blind clinical trial.Journal of applied oral science : revista FOB · 2024Trial
- In-office dental bleaching in adolescents using 6% hydrogen peroxide with different application tips: randomized clinical trial.Journal of applied oral science : revista FOB · 2023Trial
- Longevity, effectiveness, safety, and impact on quality of life of low-concentration hydrogen peroxides in-office bleaching: a randomized clinical trial.Clinical oral investigations · 2019Trial
- Validation of the brazilian version of the oral health impact profile - Aesthetic questionnaire.Brazilian dental journalTrial
- Impact of nanostructured additives in tooth bleaching agents on enhancing color change and reducing side effects: a scoping review.Clinical oral investigations · 2025Article
- Article
- Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors.Restorative dentistry & endodontics · 2023Article
- Improved esthetic efficacy and reduced cytotoxicity are achieved with a violet LED irradiation of manganese oxide-enriched bleaching gels.Lasers in medical science · 2022Article
- Manganese oxide increases bleaching efficacy and reduces the cytotoxicity of a 10% hydrogen peroxide bleaching gel.Clinical oral investigations · 2022Article
- Psychosocial impact of dental aesthetics on dental patients.International dental journal · 2020Article
- Oral status and aesthetics after nonsurgical periodontal treatment: Do patient's perception and dentist's evaluation agree?Clinical and experimental dental research · 2019Observational
- Increased whitening efficacy and reduced cytotoxicity are achieved by the chemical activation of a highly concentrated hydrogen peroxide bleaching gel.Journal of applied oral science : revista FOB · 2019Article
- The effects of at-home whitening on patients' oral health, psychology, and aesthetic perception.BMC oral health · 2018Article
- Influence of Professional Teeth Whitening on Oral Hygiene: Long-term Results.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
This study aimed to evaluate color longevity after 2 years of whitening gel (6% hydrogen peroxide (HP), blue LED/infrared laser activation system) in comparison to a control 35% concentration in a split-mouth study and investigate the long-term effect on quality of life (QOL).Thirty-one patients were treated. Whitening using 6% or 35% HP gel was performed on half of the upper jaw in each patient. The color was measured at baseline and 1 week, 1 month, 1 and 2 years after treatment using the Easyshade Vita spectrophotometer and the Vita Bleached and Vita Classical Shade Guides organized by value. During 2 years of follow-up, color was evaluated before and after dental prophylaxis. Oral Health of Impact Profile (OHIP 14) and Psychosocial Impact Dental Aesthetics Questionnaire (PIDAQ) surveys measured QOL. Nineteen patients were evaluated at the 2-year follow-up. Significant differences in ΔE were measured between the two groups at all time points (p < 0.05). No significant differences in ΔSGU were observed at any time point (p > 0.05). The positive effect of bleaching on QOL was maintained in patients treated with a low concentration of the whitening gel. The two compounds remained effective after 2 years. An objective color difference was found between the groups, but no difference was observed in subjective reports. The positive effect on QOL remained after 2 years of follow-up in this cohort of patients.ClinicalTrials.gov identifier NCT02353611.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.