ReviewCurrent reviews in musculoskeletal medicine2018
Low-Virulence Organisms and Periprosthetic Joint Infection-Biofilm Considerations of These Organisms.
Review in Current reviews in musculoskeletal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 44 citations in OpenAlex.
- Synovial Calprotectin in Suspected Periprosthetic Joint Infection After Total Knee Arthroplasty: Diagnostic Accuracy and Exploratory Adjunctive Value to Preoperative ICM Classification.Antibiotics (Basel, Switzerland) · 2026Article
- Characterization ofFrontiers in surgery · 2026Article
- Clinical application of synovial fluid albumin-to-globulin ratio as a novel biomarker in diagnosing chronic periprosthetic joint infection.Frontiers in cellular and infection microbiology · 2026Article
- Advancing diagnostics in suspected periprosthetic joint infections using synthetic synovial fluid and microcalorimetry.Journal of bone and joint infection · 2026Article
- Synovial Periprosthetic Infection Markers Show High Variability in Different Clinical and Microbiological Settings.Journal of clinical medicine · 2025Article
- Performance of established test methods for diagnosing chronic periprosthetic joint infections caused by low-virulence pathogens.Bone & joint research · 2025Article
- Timepoint of aspiration can impact diagnostic of PJI - synovial fluid analyses exhibit a high intraindividual variation in periprosthetic joint infections of the knee.Archives of orthopaedic and trauma surgery · 2025Article
- Evaluation of Risk Factors for Periprosthetic Joint Infection Following Reverse Shoulder Arthroplasty: A Multivariate Analysis Study.Journal of clinical medicine · 2025Article
- The diagnostic accuracy of blood C-reactive protein and erythrocyte sedimentation rate in periprosthetic joint infections - A 10-year analysis of 1510 revision hip and knee arthroplasties from a single orthopaedic center.Journal of orthopaedic surgery and research · 2025Article
- Role of Serum Biomarkers in Differentiating Periprosthetic Joint Infections from Aseptic Failures after Total Hip Arthroplasties.Journal of clinical medicine · 2024Article
- Management of periprosthetic joint infection of the shoulder: A narrative review.Journal of clinical orthopaedics and trauma · 2024Article
- Unexpected positive cultures in revision total knee arthroplasty after unicompartmental knee arthroplasty.International orthopaedics · 2024Article
- Is there sufficient evidence to support the use of antibiotic holiday just before the second stage of an infected total hip or knee arthroplasty revision surgery?World journal of orthopedics · 2024Article
- Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant Failure.Antibiotics (Basel, Switzerland) · 2024Article
- Fluoroscopic-guided procedures of the lower extremity.Skeletal radiology · 2023Review
- Periprosthetic joint infections of the shoulder: A 10-year retrospective analysis outlining the heterogeneity among these patients.Shoulder & elbow · 2022Article
- Evaluation of multi-sample 16S ribosomal DNA sequencing for the diagnosis of postoperative bone and joint infections during antimicrobial treatment.BMC research notes · 2022Article
- Management of Periprosthetic Hip and Knee Joint Infections With a Known Sinus Tract-A Single-Center Experience.Arthroplasty today · 2021Article
- Preliminary evaluation of a rapid lateral flow calprotectin test for the diagnosis of prosthetic joint infection.Bone & joint research · 2020Article
- Antimicrobial Silver Multilayer Coating for Prevention of Bacterial Colonization of Orthopedic Implants.Materials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThe purpose of this manuscript is to provide a critical review of peer-reviewed literature over the last 5 years related to low virulent organisms associated with periprosthetic joint infection (PJI). We evaluated the most common organisms, the diagnostic challenges, and the novel tools available in the perioperative workup of PJI as well as the current understanding of how biofilm potentiates the indolent clinical presentation and explore a possible shift in the surgical management of these patients. RECENT
findingsBiofilm actively prevents macrophage phagocytosis by suppressing proinflammatory activity through the recruitment of myeloid-derived suppressor cells. Given the appropriate host and organism conditions, increased utilization of one-stage exchange arthroplasty in the surgical treatment of these low virulent infections may be on the rise. Biomarkers and molecular techniques offer encouraging results to diagnose low virulent organisms and future research focused on the disruption of biofilm may ultimately give rise to improved treatment strategies.
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