Evidence map›Paper›PMID 29961172›Full record

ArticleSurgery today2018

The validity of the surgical indication for intraductal papillary mucinous neoplasm of the pancreas advocated by the 2017 revised International Association of Pancreatology consensus guidelines.

Yusuke Watanabe, Sho Endo, Kazuyoshi Nishihara, Keijiro Ueda, Mari Mine, Sadafumi Tamiya, Toru Nakano, Masao Tanaka

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pancreatic Cysts in the Elderly.Current treatment options in gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yusuke WatanabeDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan. wyuusuke@surg1.med.kyushu-u.ac.jp.
Sho EndoDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Kazuyoshi NishiharaDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Keijiro UedaDepartment of Gastroenterology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Mari MineDepartment of Pathology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Sadafumi TamiyaDepartment of Pathology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Toru NakanoDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokrakita-ku, Kitakyushu, 802-0077, Japan.
Masao TanakaDepartment of Surgery, Shimonoseki City Hospital, 1-13-1 Koyo-cho, Shimonoseki, 750-8520, Japan.
Kitakyushu Municipal Medical Center · JPShimonoseki City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was performed to evaluate the surgical indication for intraductal papillary mucinous neoplasm (IPMN) advocated by the 2017 revised International Association of Pancreatology consensus guidelines (IAPCG2017).

methodsThe medical records of 63 patients who underwent pancreatectomy for IPMN were retrospectively reviewed.

resultsThirteen patients had main-duct IPMN, 25 had mixed IPMN, and 25 had branch-duct IPMN with frequencies of high-grade dysplasia or invasive carcinoma of 62, 24, and 28%, respectively. The sensitivity and specificity of high-risk stigmata for high-grade dysplasia or invasive carcinoma advocated by the IAPCG2017 were 90 and 67%, respectively. Of 17 patients with invasive carcinoma, all patients had high-risk stigmata, and 16 had an enhanced mural nodule (MN) of ≥ 5 mm. The sensitivity and specificity of a ≥ 5-mm enhanced MN for predicting invasive carcinoma were 94% and 87%, respectively.

conclusionsIntroducing a size threshold for enhanced MNs into the assessment of high-risk stigmata increases the specificity without jeopardizing the sensitivity. The surgical indication for any type of IPMN may be determined using only a ≥ 5-mm enhanced MN. When the type of IPMN is classified strictly, about half of IPMNs are mixed type, and most are benign. The surgical indication for mixed IPMN should be reconsidered.

Indexed as

PancreatectomyPractice Guidelines as TopicAdenocarcinoma, MucinousAdultAgedAged, 80 and overCarcinoma, Pancreatic DuctalCarcinoma, PapillaryFemaleHumansMaleMiddle AgedNeoplasm InvasivenessNeoplasms, Cystic, Mucinous, and SerousNeoplasms, Multiple PrimaryPancreatic NeoplasmsHigh-risk stigmataInternational consensus guidelinesIntraductal papillary mucinous neoplasmasWorrisome feature

Identifiers

PMID29961172
OpenAlexW2810871014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.