Evidence map›Paper›PMID 29961155›Full record

ArticleClinical and experimental nephrology2018

Calcium-sensing receptor (CaSR) modulates vacuolar H

Priscilla Marys Costa Dos Santos, Deividi Amaral, Ana Lucia Tararthuch, Ricardo Fernandez

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In one paragraph

Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Priscilla Marys Costa Dos SantosDepartamento de Fisiologia, Setor de Ciências Biológicas, UFPR, Centro Politécnico s/n., Jd. das Américas, Postal Box: 19031, Curitiba, PR, 81531-990, Brazil.
Deividi AmaralDepartamento de Fisiologia, Setor de Ciências Biológicas, UFPR, Centro Politécnico s/n., Jd. das Américas, Postal Box: 19031, Curitiba, PR, 81531-990, Brazil.
Ana Lucia TararthuchDepartamento de Fisiologia, Setor de Ciências Biológicas, UFPR, Centro Politécnico s/n., Jd. das Américas, Postal Box: 19031, Curitiba, PR, 81531-990, Brazil.
Ricardo FernandezDepartamento de Fisiologia, Setor de Ciências Biológicas, UFPR, Centro Politécnico s/n., Jd. das Américas, Postal Box: 19031, Curitiba, PR, 81531-990, Brazil. ricfer@ufpr.br.ORCID http://orcid.org/0000-0002-6760-3952
Universidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe calcium-sensing receptor (CaSR) is localized in the apical membrane of proximal tubules in close proximity to the transporters responsible for proton secretion. Therefore, the aim of the present study was to analyze the effects of CaSR stimulation on the biochemical activity of the vacuolar H

methodsBiochemical activity of H

resultsA significant increase of vacuolar H

conclusionCaSR stimulation induces an increase in the vacuolar H

Indexed as

AnimalsCalciumCells, CulturedHydrogen-Ion ConcentrationKidney Tubules, ProximalNeomycinOpossumsReceptors, Calcium-SensingType C PhospholipasesVacuolar Proton-Translocating ATPasesCalciumNeomycinReceptors, Calcium-SensingType C PhospholipasesVacuolar Proton-Translocating ATPasesCalcium-sensing receptor (CaSR)H+-ATPaseIntracellular calciumOKP cellsProximal tubule

Identifiers

PMID29961155
OpenAlexW2809955414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.