Evidence map›Paper›PMID 29961110›Full record

Trial reportInternational urogynecology journal2018

RCT of vaginal extraperitoneal uterosacral ligament suspension (VEULS) with anterior mesh versus sacrocolpopexy: 4-year outcome.

Lin Li Ow, Yik N Lim, Joseph Lee, Christine Murray, Elizabeth Thomas, Alison Leitch, Anna Rosamilia, Peter L Dwyer

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Surgery for women with apical vaginal prolapse.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Review
  3. Article
  4. Sacrocolpopexy: The Way I Do It.International urogynecology journal · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lin Li OwDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia. owlinli@yahoo.com.ORCID http://orcid.org/0000-0002-1226-1692
Yik N LimDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.
Joseph LeeDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.
Christine MurrayDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.
Elizabeth ThomasDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.
Alison LeitchMonash Medical Centre, Clayton, Victoria, Australia.
Anna RosamiliaMonash Medical Centre, Clayton, Victoria, Australia.
Peter L DwyerDepartment of Urogynaecology, Mercy Hospital for Women, 163 Studley Road, Heidelberg, Victoria, 3084, Australia.
Mercy Hospital for Women · AUMonash Medical Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThis study assessed the safety and efficacy of vaginal extraperitoneal uterosacral ligament suspension (VEULS) with anterior overlay mesh versus sacrocolpopexy (SCP) for posthysterectomy vault prolapse.

methodsThis was a multicenter randomized trial of women with posthysterectomy vault prolapse stage >2 according to the Pelvic Organ Prolapse Quantification (POP-Q) system. Primary outcome was a composite of no vaginal bulge symptoms, no anatomical recurrence in the anterior or apical compartment at or beyond the hymenal ring, and no surgical retreatment for prolapse 12 months postsurgery. Secondary outcomes were peri- and postoperative complications, changes in prolapse, and urogenital and sexual symptoms at 12, 24, and 48 months based on the Pelvic Floor Distress Inventory (PFDI)-20.

resultsBetween 2006 and 2011, 82 eligible women were randomized: 39 received VEULS and 43 received SCP. Primary composite outcome at 12 months for success was 41% for VEULS and 65% for SCP [odds ratio (OR 2.68, p = 0.03)]. Perioperative complications were more common in the SCP group. C-point was higher for SCP (-6.0 VEULS vs -8.0 SCP, p = 0.005) and total vaginal length (TVL) was longer for SCP (8.0 VEULS vs 9.0 SCP, p = 0.05). Cumulative mesh exposure rate at 4 years was similar between the uterosacral [4/39 (10.3%)] and sacrocolpopexy [4/43 (9.3%)] groups, bearing in mind that not all patients were examined at 4 years. Subjective outcomes derived from three domains of the PFDI-20 were similar at 12, 24, 48 months. Postoperative Pelvic Organ Prolapse Distress Inventory (POPDI) score improved similarly for both groups at all timepoints, with the minimally important difference of at least 21 reached for both groups.

conclusionsComposite outcome of success was better for SCP at 12 months, but subjective outcomes for prolapse at all timepoints over 4 years for VEULS and SCP were not significantly different.

Indexed as

Surgical MeshAgedColposcopyFemaleHumansHysterectomyLigamentsMiddle AgedPelvic FloorPelvic Organ ProlapsePeritoneumPostoperative ComplicationsSacrumTime FactorsTreatment OutcomeUterusDyspareuniaMesh exposureRandomized controlled trialRecurrent prolapseSacrocolpopexyTransvaginal mesh

Identifiers

PMID29961110
OpenAlexW2810392286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.