Evidence map›Paper›PMID 29961018›Full record

ArticleBMJ open2018

Development and feasibility of a guided and tailored internet-based cognitive-behavioural intervention for kidney donors and kidney donor candidates.

Lieke Wirken, Henriët van Middendorp, Christina W Hooghof, Tamara E Bremer, Sabine P F Hopman, Karlijn A M I van der Pant, Andries J Hoitsma, Luuk B Hilbrands, Andrea W M Evers

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Lieke WirkenInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.ORCID 0000-0002-1185-1383
Henriët van MiddendorpInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
Christina W HooghofDepartment of Nephrology, Radboud university medical center, Nijmegen, The Netherlands.
Tamara E BremerInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
Sabine P F HopmanDepartment of Nephrology, Radboud university medical center, Nijmegen, The Netherlands.
Karlijn A M I van der PantDepartment of Internal Medicine/Nephrology, Renal Transplant Unit, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Andries J HoitsmaDepartment of Nephrology, Radboud university medical center, Nijmegen, The Netherlands.
Luuk B HilbrandsDepartment of Nephrology, Radboud university medical center, Nijmegen, The Netherlands.
Andrea W M EversInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands.
Leiden University · NLRadboud University Nijmegen · NLAmsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLiving donor kidney transplantation is currently the preferred treatment for patients with end-stage renal disease. A subgroup of the kidney donor population experiences adjustment problems during or after the donation procedure (eg, anxiety or fatigue). There is a need for evidence-based interventions that decrease donation-related difficulties before or after donation. In the current study, a guided and tailored internet-based cognitive-behavioural therapy (ICBT) intervention for donors and donor candidates was developed and the feasibility and perceived effectiveness were evaluated.

designPilot study including qualitative and quantitative research methods for intervention development and evaluation.

settingLiving kidney donor population of two Dutch transplantation centres.

participantsDonors and healthcare professionals participated in focus group interviews conducted to identify intervention themes and to map attitudes towards internet-based interventions. In a pilot feasibility study, 99 donors and donor candidates participated, of whom 38 completed the screening. Eight donors or donor candidates with a risk profile (ie, impaired mental health-related quality of life (HRQoL)) received and evaluated the intervention.

interventionsA guided and tailored ICBT intervention for donors and donor candidates was developed. Donation-related treatment modules, assignments and psychoeducation were integrated within an existing disease-generic ICBT intervention. OUTCOME MEASURES: HRQoL, anxiety and depression were assessed before and after the ICBT intervention. Additional questionnaires were included to identify specific problem areas of donor functioning to tailor the ICBT intervention to the donor's needs.

resultsDifferent intervention themes were derived from the focus group interviews (eg, physical limitations, and donation-specific emotional and social-relational problems). Participants were satisfied about the intervention content (7.7±0.8 on a 0-10 scale) and the therapeutic relationship (4.4±0.6 on a 1-5 scale), and indicated an improvement on domains of their treatment goals (3.2±0.7 on a 1-4 scale).

conclusionThis study showed positive evaluations concerning both feasibility and perceived effectiveness of the tailored ICBT intervention in kidney donors and donor candidates, in line with previous studies using comparable ICBT treatment protocols in other populations. Future research should examine the possibilities of integrating the intervention into psychosocial care for kidney donors.

Indexed as

InternetKidney TransplantationTelemedicineAdultAgedAnxietyCognitive Behavioral TherapyDepressionFeasibility StudiesFemaleHumansLiving DonorsMaleMiddle AgedNetherlandsPersonal Satisfactioncognitive behavioral therapyehealthinternet-based interventionliving kidney donorsquality of life

Identifiers

PMID29961018
PMCPMC6042571
OpenAlexW2810130832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.