Evidence map›Paper›PMID 29960991›Full record

ArticleJournal of the American Heart Association2018

Cerebral Protection During Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Heart Disease.

Christian-Hendrik Heeger, Andreas Metzner, Michael Schlüter, Andreas Rillig, Shibu Mathew, Roland Richard Tilz, Peter Wohlmuth, Maria E Romero, Renu Virmani, Thomas Fink and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Real-world characteristics and management of ventricular tachycardias in ICD patients: Data from the VIDEO registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  7. Cerebral embolic protection during transcatheter heart interventions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Review
  8. Review
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  12. Complications of catheter ablation for ventricular tachycardia.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Christian-Hendrik HeegerDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany christian.heeger@gmx.net.
Andreas MetznerDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Michael SchlüterAsklepios Proresearch, Hamburg, Germany.
Andreas RilligDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Shibu MathewDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Roland Richard TilzUniversity Heart Center Luebeck, Luebeck, Germany.
Peter WohlmuthAsklepios Proresearch, Hamburg, Germany.
Maria E RomeroCV Path Institute, Inc., Gaithersburg, MD.
Renu VirmaniCV Path Institute, Inc., Gaithersburg, MD.
Thomas FinkDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Bruno ReissmannDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Christine LemesDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Tilman MaurerDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Francesco SantoroDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Tobias SchmidtDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Alexander GhanemDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Christian FrerkerDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Karl-Heinz KuckDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Feifan OuyangDepartment for Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Asklepios Klinik St. Georg · DEAsklepios · DECVPath Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation of ventricular tachycardia (VT) is associated with the risk of cerebral embolism. The origin of periprocedural brain embolism in the setting of VT ablation is often unknown and strategies to avoid it are sparse. The aim of this study was to assess the safety and feasibility of an endovascular 2-filter-based cerebral protection system (CPS) in left ventricular VT ablation procedures in patients with ischemic heart disease. Furthermore, histopathological correlates of periprocedural embolization were investigated. METHODS AND

resultsIn this pilot study, 11 patients with ischemic heart disease and sustained VT underwent left ventricular catheter ablation under CPS surveillance. The placement of the CPS was conducted before the ablation procedure via the right radial artery. The VT ablation procedure was performed via a combined transaortic and transseptal approach. All VTs were successfully ablated. Placement and retrieval of the CPS was successful and safe in all cases. No periprocedural complications related to the CPS were observed and no periprocedural transient ischemic attack or stroke occurred. Debris captured by the CPS was detected in all patients. Histology revealed that acute thrombus was the most common type of debris (91%), followed by arterial wall tissue (73%) and foreign material (55%). Less frequently found were myocardium (27%), calcification (9%), necrotic core (9%), and valve tissue (9%).

conclusionsCerebral protection during VT ablation seems to be safe and feasible. Ablation procedures of VT are associated with embolization of embolic debris, which was found in every patient.

Indexed as

Embolic Protection DevicesAgedCatheter AblationCerebrovascular CirculationFeasibility StudiesFemaleHumansIntracranial EmbolismMaleMyocardial IschemiaPilot ProjectsProsthesis DesignProtective FactorsRisk FactorsStrokeTachycardia, Ventricularcatheter ablationhistopathologystroke preventionventricular tachycardia

Identifiers

PMID29960991
PMCPMC6064920
OpenAlexW2810953203

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.