ArticleJournal of applied clinical medical physics2018
Safety and benefit of using a virtual bolus during treatment planning for breast cancer treated with arc therapy.
Article in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Dosimetric and radiobiological evaluations as well as technical aspects of left breast treatment employing DIBH with SGRT in radiotherapy with IMRT step and shoot, IMRT Dynamic MLC and VMAT.Journal of applied clinical medical physics · 2026Article
- Development of a customized three-dimensional bolus using transparent gel wax and its application in electron beam therapy.Physical and engineering sciences in medicine · 2026Article
- Dosimetric effects of internal margin, auto flash, and virtual bolus in VMAT-based whole-breast radiotherapy under motion variations.Journal of applied clinical medical physics · 2026Article
- Performance evaluation of a new automated skin flash method for radiotherapy of breast cancer.Physics and imaging in radiation oncology · 2025Article
- A robust planning approach for respiratory motion in accelerated partial breast irradiation using volumetric modulated arc therapy.Journal of radiation research · 2025Article
- Comprehensive dosimetric comparison of halcyon 3.0 versus truebeam for breast cancer volumetric modulated arc therapy plans.Frontiers in oncology · 2025Article
- Post-mastectomy radiotherapy: Impact of bolus thickness and irradiation technique on skin dose.Zeitschrift fur medizinische Physik · 2024Article
- Evaluation of radiotherapy planning approaches for head and neck patients with tumors close to the skin surface.Journal of applied clinical medical physics · 2024Article
- Hybrid VMAT-3DCRT as breast cancer treatment improvement tool.Scientific reports · 2024Article
- Clinical Application of a Customized 3D-Printed Bolus in Radiation Therapy for Distal Extremities.Life (Basel, Switzerland) · 2023Article
- Retrospective evaluation of a robust hybrid planning technique established for irradiation of breast cancer patients with included mammary internal lymph nodes.Radiation oncology (London, England) · 2022Article
- Split-VMAT technique to control the deep inspiration breath hold time for breast cancer radiotherapy.Radiation oncology (London, England) · 2021Article
- Article
- Treatment planning comparison of volumetric modulated arc therapy with the trilogy and the Halcyon for bilateral breast cancer.Radiation oncology (London, England) · 2021Article
- In search of a one plan solution for VMAT post-mastectomy chest wall irradiation.Journal of applied clinical medical physics · 2020Article
- Validation of the Gel & Wax Boluses and Comparison of their Dosimetric Performance with Virtual Bolus.Journal of biomedical physics & engineering · 2019Article
- In regards to Bogue J, Wan J, Lavey RS, Parsai EI. Dosimetric comparison of VMAT with integrated skin flash to 3D field-in-field tangents for left breast irradiation. Journal of applied clinical medical physics. 2019 Feb;20(2):24-9.Journal of applied clinical medical physics · 2019Article
- Evaluation of organ motion-based robust optimisation for VMAT planning for breast and internal mammary chain radiotherapy.Clinical and translational radiation oncology · 2019Article
- Superficial Dosimetry Study of the Frequency of Bolus Using in Volumetric Modulated Arc Therapy after Modified Radical Mastectomy.Technology in cancer research & treatmentArticle
- Planning System-dependent Recommendations of Intensity-modulated Technique for Breast Radiotherapy: A Literature Review-based Adaptation and Institutional Dosimetric Experience from a Large-volume Tertiary Cancer Care Hospital.Journal of medical physicsReview
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluates the benefit of a virtual bolus method for volumetric modulated arc therapy (VMAT) plan optimization to compensate breast modifications that may occur during breast treatment.
methodsTen files were replanned with VMAT giving 50 Gy to the breast and 47 Gy to the nodes within 25 fractions. The planning process used a virtual bolus for the first optimization, then the monitors units were reoptimized without bolus, after fixing the segments shapes. Structures and treatment planning were exported on a second scanner (CT) performed during treatment as a consequence to modifications in patient's anatomy. The comparative end-point was clinical target volume's coverage. The first analysis compared the VMAT plans made using the virtual bolus method (VB-VMAT) to the plans without using it (NoVB-VMAT) on the first simulation CT. Then, the same analysis was performed on the second CT. Finally, the level of degradation of target volume coverage between the two CT using VB-VMAT was compared to results using a standard technique of forward-planned multisegment technique (Tan-IMRT).
resultsUsing a virtual bolus for VMAT does not degrade dosimetric results on the first CT. No significant result in favor of the NoVB-VMAT plans was noted. The VB-VMAT method led to significant better dose distribution on a second CT with modified anatomies compared to NoVB-VMAT. The clinical target volume's coverage by 95% (V95%) of the prescribed dose was 98.9% [96.1-99.6] on the second CT for VB-VMAT compared to 92.6% [85.2-97.7] for NoVB-VMAT (P = 0.0002). The degradation of the target volume coverage for VB-VMAT is not worse than for Tan-IMRT: the median differential of V95% between the two CT was 0.9% for VMAT and 0.7% for Tan-IMRT (P = 1).
conclusionThis study confirms the safety and benefit of using a virtual bolus during the VMAT planning process to compensate potential breast shape modifications.
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