Observational studyHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2018
Prevalence and Comorbidities of Resistant Hypertension: A Collaborative Population-Based Observational Study.
Observational study in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Prevalence of and associated factors for resistant hypertension in primary care settings: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- Prevalence of Comorbidity and Associated Factors Among Patients With Hypertension in Health Facilities of Southern Ethiopia.BioMed research international · 2026Article
- Characterizing apparent treatment resistant hypertension in the United States: insights from the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Prevalence and associated risk factors of resistant hypertension among Chinese hypertensive patients in primary care setting.BMC primary care · 2024Article
- Resistant Hypertension and Related Outcomes in a Cohort of Patients with Cardiorenal Multimorbidity Hospitalized in an Internal Medicine Ward.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Article
- Hypertension, uncontrolled hypertension and resistant hypertension: prevalence, comorbidities and prescribed medications in 228,406 adults resident in urban areas. A population-based observational study.Internal and emergency medicine · 2023Observational
- Professionals' and Patients' Perspectives on Criteria for Referring Hypertensive Patients to Comprehensive Medication Management Services in Public Primary Health Care.International journal of environmental research and public health · 2023Article
- Lobar intracerebral hemorrhage and risk of subsequent uncontrolled blood pressure.European stroke journal · 2022Article
- Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor.Scientific reports · 2022Article
- The Burden of Resistant Hypertension Across the World.Current hypertension reports · 2022Review
- The association between type 2 diabetes and anhedonic subtype of major depression in hypertensive individuals.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResistant hypertension, is a clinical condition that may confer high cardiovascular risk. Aim of the observational study was to evaluate the prevalence of resistant hypertension, and the association with cardiovascular risk factors or diseases in the Verona urban area. DESIGN AND
methodsEleven family doctors retrieved anonymised data concerning blood pressure, diagnosis of hypertension and treatments from a population of 17,502 adult subjects. The prevalence of resistant hypertension was estimated considering patients who had been consecutively treated with at least four antihypertensive medications, regardless of blood pressure values. Further search concerning the clinical characteristics associated with resistant hypertension was performed in a random subsample of 55 patients.
resultsThe prevalence of hypertension was 21.9%, that of resistant hypertension was 2.1%, approximately 10% of the whole hypertensive population. High prevalence of diabetes mellitus (53%) and hyperlipidemia (83%) was found in association with resistant hypertension. As for end organ damage, high prevalence of carotid artery stenosis (45%), ischemic heart disease (43%) and left ventricular hypertrophy (40%) was observed in patients with resistant hypertension. Blood pressure was higher than 140/90 mmHg in 58% of patients in spite of treatment with four or more different antihypertensive drugs. The average age, systolic and pulse pressure were significantly higher in the subgroup of patients with resistant hypertension.
conclusionsPatients with resistant hypertension are characterised by a higher systolic and pulse pressure and a very high attributable cardiovascular risk, due to high prevalence of cardiovascular risk factors and overt organ damage and cardiovascular disease.
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