ReviewCurrent heart failure reports2018
Identifying and Managing Hibernating Myocardium: What's New and What Remains Unknown?
Review in Current heart failure reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Safety and therapeutic potential of allogeneic adipose-derived stem cell spray transplantation in ischemic cardiomyopathy: a phase I clinical trial.Journal of translational medicine · 2024Trial
- Role of Coronary Revascularization in Patients with Ischemic Heart Disease and Heart Failure with Reduced Ejection Fraction.Journal of clinical medicine · 2026Review
- A Middle-Aged Man With Pulseless VT and Dual Pathology: Anomalous Left Main Coronary Artery From Right Coronary Cusp With Transseptal Course and Underlying Dilated Cardiomyopathy.Clinical case reports · 2025Article
- The Role of Imaging Modalities in Estimating Myocardial Viability: A Narrative Review.Journal of clinical medicine · 2025Review
- Myocardial Viability: Evolving Insights and Challenges in Revascularization and Functional Recovery.Journal of cardiovascular development and disease · 2025Review
- Clinical use of cardiac 18 F-FDG viability PET: a retrospective study of 44 patients undergoing post-test revascularization.The international journal of cardiovascular imaging · 2022Article
- Predictive value of the echocardiographic noninvasive myocardial work index for left ventricular reverse remodeling in patients with multivessel coronary artery disease after percutaneous coronary intervention.Quantitative imaging in medicine and surgery · 2022Article
- Temporal trends in characteristics and outcome of heart failure patients with and without significant coronary artery disease.ESC heart failure · 2022Article
- Strategies for Imaging Metabolic Remodeling of the Heart in Obesity and Heart Failure.Current cardiology reports · 2022Review
- Comparative Analysis of Myocardial Viability Multimodality Imaging in Patients with Previous Myocardial Infarction and Symptomatic Heart Failure.Medicina (Kaunas, Lithuania) · 2022Article
- Myocardial viability testing: all STICHed up, or about to be REVIVED?European heart journal · 2022Article
- Relief of Ischemia in Ischemic Cardiomyopathy.Current cardiology reports · 2021Review
- A Pilot Evaluation Study of Diffuse Coronary Arterial Contraction Causing Ischemia by Double Measurement of Left Ventriculography Before and After Intracoronary Administration of Nitrates.Circulation reports · 2021Article
- Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial.Molecular therapy. Methods & clinical development · 2020Article
- Band on the run: insights into right ventricular reverse remodelling.Cardiovascular research · 2020Article
- Do critical care patients hibernate? Theoretical support for less is more.Intensive care medicine · 2020Article
- Stunned and Hibernating Myocardium: Where Are We Nearly 4 Decades Later?Journal of the American Heart Association · 2020Review
- The Role of Troponin for Acute Heart Failure.Current heart failure reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewHibernation is an important and reversible cause of myocardial dysfunction in ischaemic heart failure. RECENT
findingsHibernation is an adaptive process that promotes myocyte survival over maintaining contractile function. It is innate to mammalian physiology, sharing features with physiological hibernation in other species. Advanced imaging methods have reasonable accuracy in identifying hibernating myocardium. Novel superior hybrid methods may provide diagnostic potential. New evidence supports the role of surgical revascularisation in ischaemic heart failure, but the role of viability tests in planning such procedures remains unclear. Research to date has exclusively involved patients with ambulatory heart failure: Investigating the role of hibernation in ADHF is a key avenue for the future. Whilst our understanding of hibernation pathophysiology has improved dramatically, the clinical utility of identifying and targeting hibernation remains unclear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.