ArticleSocial psychiatry and psychiatric epidemiology2018
Which mental disorders are associated with the greatest impairment in functioning?
Article in Social psychiatry and psychiatric epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Prevention of mental disorders after exposure to natural hazards: a meta-analysis.BMJ mental health · 2025Pooled it
- Prevalence of social anxiety disorder and symptoms among Chinese children, adolescents and young adults: A systematic review and meta-analysis.Frontiers in psychology · 2022Pooled it
- Role impairment of patients with mental disorders and physical diseases in China: Results from the China Mental Health Survey.Chinese medical journal · 2026Article
- The Impact of Pre-Existing Psychiatric Disorders on Gastric Cancer Stage and Mortality in Older Adults.Cancer medicine · 2026Article
- Mental Health of Forcibly Displaced Persons from Nagorno-Karabakh: A Cross-Sectional Study.Consortium psychiatricum · 2025Article
- Effects and Side Effects in a Short Work Coaching for Participants with and without Mental Illness.Behavioral sciences (Basel, Switzerland) · 2024Article
- Article
- The Mental Health of Refugees and Forcibly Displaced People: A Narrative Review.Consortium psychiatricum · 2024Review
- Occupational performance and satisfaction of individuals with mental disorders in Jordan: A cross-sectional study.The British journal of occupational therapy · 2022Article
- Hoarding symptoms are associated with higher rates of disability than other medical and psychiatric disorders across multiple domains of functioning.BMC psychiatry · 2022Article
- Impact of the COVID-19 pandemic on older adults mental health services: A mixed methods study.International journal of geriatric psychiatry · 2021Article
- Functional Disability in Patients with Mood Disorders at St Paul's Hospital Psychiatry Clinic, Addis Ababa, Ethiopia, 2019.Patient related outcome measures · 2021Article
- Anxiety, depression and post-traumatic stress disorder in refugees resettling in high-income countries: systematic review and meta-analysis.BJPsych open · 2020Article
- The role impairment associated with mental disorder risk profiles in the WHO World Mental Health International College Student Initiative.International journal of methods in psychiatric research · 2019Article
- Time in remission from depression predicts cognitive-affective regulation dynamics in everyday life.Journal of clinical and experimental neuropsychologyArticle
- Self-Care Capacity and Its Relationship to Age, Disability, and Perceived Well-Being in Medicare Beneficiaries.Nursing researchArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe objective of this study is to estimate the comparative associations of mental disorders with three measures of functional impairment: the Global Assessment of Functioning (GAF); the number of days in the past 12 months of total inability to work or carry out normal activities because of emotions, nerves, or mental health (i.e., days out of role); and a modified version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0).
methodsSecondary data analysis of the linked Mental Health Surveillance Study and the National Survey on Drug Use and Health (n = 5653), nationally representative population surveys conducted in the United States. Generalized linear models assessed the independent effects of mental disorders on each measure of functional impairment, controlling for mental disorder comorbidity, physical health disorders, and sociodemographic factors.
resultsThe results varied across measures of functional impairment. However, mood disorders generally tended to be associated with the greatest functional impairment, anxiety disorders with intermediate impairment, and substance use disorders with the least impairment. All 15 disorders were significantly associated with the GAF score in multiple regression models, eight disorders were significantly associated with the WHODAS score, and three disorders were significantly associated with days out of role.
conclusionsOur results highlight the value of complementary measures of functional impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.