Evidence map›Paper›PMID 29959417›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2018

Inflammatory mediators reduce surface PrP

Bezawit W Megra, Eliseo A Eugenin, Joan W Berman

Open access · bronzeAbstract read
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Prion Protein at the Leading Edge: Its Role in Cell Motility.International journal of molecular sciences · 2020
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bezawit W MegraDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Eliseo A EugeninPublic Health Research Institute (PHRI), Newark, NJ, 07103, USA.
Joan W BermanDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. joan.berman@einstein.yu.edu.
Albert Einstein College of Medicine · USRutgers, The State University of New Jersey · US

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Kathryn M. Anastos · 2017 to 2026
$28.3M
Astrocyte connexin43 containing channels amplify CNS dysfunction in NeuroAIDSR01MH096625 · NIMH · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI EUGENIN, ELISEO A · 2012 to 2020
$4.5M
Mechanisms of HAD:Role of CCL2 BBB & HIV InfectionR01MH075679 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2006 to 2016
$4.0M
Impact of illicit drugs, HIV, and ART on neuroinflammation and BBB disruptionR01DA044584 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER, GOLDSTEIN, HARRIS · 2017 to 2021
$4.0M
Role of pannexin-1 hemichannels in NeuroAIDSR01NS105584 · NINDS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI EUGENIN, ELISEO A · 2017 to 2021
$3.2M
Role of cellular prion protein in the pathogenesis of NeuroAIDSR01MH090958 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2011 to 2015
$1.9M
Dopamine alters CNS migration of uninfected and HIV infected leukocytes to SDF-1R01DA025567 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BERMAN, JOAN WEINBERGER · 2008 to 2012
$1.7M
Mechanisms of HIV Tat regulation of macrophage gene expression in neuroAIDSR21MH102113 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2014 to 2015
$459k
NIAID NIH HHS P30 AI124414NIDA NIH HHS R01 DA025567NIDA NIH HHS R01 DA044584NIMH NIH HHS R01 MH075679NIMH NIH HHS R01 MH090958NIMH NIH HHS R01 MH096625NIMH NIH HHS R21 MH102113NINDS NIH HHS R01 NS105584
6 · The paper itself

Abstract

The cellular prion protein (PrP

Indexed as

Blood-Brain BarrierCells, CulturedClaudin-5Endothelial CellsHumansInflammationOccludinPrPC ProteinsTumor Necrosis Factor-alphaVascular Endothelial Growth Factor AClaudin-5CLDN5 protein, humanOccludinOCLN protein, humanPrPC ProteinsTumor Necrosis Factor-alphaVascular Endothelial Growth Factor A

Identifiers

PMID29959417
PMCPMC6163073
OpenAlexW2810479925

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.