Evidence map›Paper›PMID 29959414›Full record

ArticleLeukemia2018

Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS.

Michael O Alberti, Sridhar Nonavinkere Srivatsan, Jin Shao, Samantha N McNulty, Gue Su Chang, Christopher A Miller, Jennifer B Dunlap, Fei Yang, Richard D Press, Qingsong Gao and 4 more

Abstract read
In one paragraph

Article in Leukemia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. U2af1Leukemia · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Epigenetic regulation by ASXL1 in myeloid malignancies.International journal of hematology · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. ASXL1/2 mutations and myeloid malignancies.Journal of hematology & oncology · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Michael O AlbertiDepartment of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-4269-4701
Sridhar Nonavinkere SrivatsanDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Jin ShaoDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Samantha N McNultyDepartment of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Gue Su ChangDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Christopher A MillerDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-4266-6700
Jennifer B DunlapDepartment of Pathology, Oregon Health & Science University, Portland, OR, USA.
Fei YangDepartment of Pathology, Oregon Health & Science University, Portland, OR, USA.
Richard D PressDepartment of Pathology, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-2103-5144
Qingsong GaoDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Li DingDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-1517-2975
Jonathan W HeuselDepartment of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Eric J DuncavageDepartment of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Matthew J WalterDivision of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. mjwalter@wustl.edu.ORCID http://orcid.org/0000-0002-7753-1091

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Specimen Acquistition and Expression ProfilingP01CA101937 · NCI · WASHINGTON UNIVERSITY · PI LEY, TIMOTHY J. · 2003 to 2023
$58.8M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI TODD A FEHNIGER · 2013 to 2026
$31.6M
COMPREHENSIVE INFORMATIC ANALYSES OF AML GENOMES AND EPIGENOMESR50CA211782 · NCI · WASHINGTON UNIVERSITY · PI Christopher A Miller · 2017 to 2026
$1.5M
NCI NIH HHS P01 CA101937NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA171963NCI NIH HHS R50 CA211782
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene DuplicationMutationArtifactsBiomarkers, TumorDiagnosis, DifferentialHematologic NeoplasmsHigh-Throughput Nucleotide SequencingHumansMolecular Diagnostic TechniquesMyeloproliferative DisordersPrognosisRepressor ProteinsASXL1 protein, humanBiomarkers, TumorRepressor Proteins

Identifiers

PMID29959414
PMCPMC6402595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.