Evidence map›Paper›PMID 29959336›Full record

ArticleScientific reports2018

Mapping of brain tissue hematocrit in glioma and acute stroke using a dual autoradiography approach.

A Broisat, B Lemasson, M Ahmadi, N Collomb, S Bacot, A Soubies, D Fagret, C Rémy, C Ghezzi, E L Barbier

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Effects of mild hypoxia on oxygen extraction fraction responses to brain stimulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

A BroisatUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
B LemassonUniv. Grenoble Alpes, Inserm, U1216, GIN, F-38000, Grenoble, France.ORCID 0000-0003-0446-3531
M AhmadiUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
N CollombUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, IRMaGe, CNRS, F-38000, Grenoble, France.
S BacotUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
A SoubiesUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
D FagretUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
C RémyUniv. Grenoble Alpes, Inserm, U1216, GIN, F-38000, Grenoble, France.
C GhezziUniv. Grenoble Alpes, Inserm, CHU Grenoble Alpes, U1039, LRB, F-38000, Grenoble, France.
E L BarbierUniv. Grenoble Alpes, Inserm, U1216, GIN, F-38000, Grenoble, France. emmanuel.barbier@univ-grenoble-alpes.fr.
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematocrit (Hct) determines the ability of blood to carry oxygen. While changes in systemic Hct are known to impact stroke or tumor control, changes in local (tissue) Hct (tHct) induced by these diseases have however received little attention. In this study, we evaluate tHct in acute stroke and in glioma models using a new approach to map tHct across the brain, a dual isotope autoradiography, based on injections of

Indexed as

AutoradiographyAnimalsBrain MappingGliomaHematocritMaleRatsStroke

Identifiers

PMID29959336
PMCPMC6026160
OpenAlexW2810492269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.