Evidence map›Paper›PMID 29959216›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Targeting Micrometastases: The Effect of Heterogeneous Radionuclide Distribution on Tumor Control Probability.

Nadia Falzone, Boon Quan Lee, Sarah Able, Javian Malcolm, Samantha Terry, Yasir Alayed, Katherine Anne Vallis

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. MIRD Pamphlet No. 27: MIRDcell V3, a Revised Software Tool for Multicellular Dosimetry and Bioeffect Modeling.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  10. Article
  11. Article
  12. EANM position paper on the role of radiobiology in nuclear medicine.European journal of nuclear medicine and molecular imaging · 2021
    Article
  13. Mars Shot for Nuclear Medicine, Molecular Imaging, and Molecularly Targeted Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Review
  14. Imaging DNA Damage Repair In Vivo AfterJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  15. Article
  16. Auger electrons for cancer therapy - a review.EJNMMI radiopharmacy and chemistry · 2019
    Review
  17. Antitumor Activity of Auger Electron EmitterFrontiers in pharmacology · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nadia FalzoneUnivesrity of Oxford, United Kingdom.
Boon Quan LeeUniversity of Oxford, United Kingdom.
Sarah AbleUniversity of Oxford, United Kingdom.
Javian MalcolmUniversity of Oxford, United Kingdom.
Samantha TerryUniversity of Oxford, United Kingdom.
Yasir AlayedUniversity of Oxford, United Kingdom.
Katherine Anne VallisUniversity of Oxford, United Kingdom.
University of Oxford · GBCRUK/MRC Oxford Institute for Radiation Oncology · GB

Funding

Cancer Research UK 22906
6 · The paper itself

Abstract

The spatial distribution of radiopharmaceuticals that emit short-range high linear-energy-transfer electrons greatly affects the absorbed dose and their biological effectiveness. The purpose of this study was to investigate the effect of heterogeneous radionuclide distribution on tumor control probability (TCP) in a micrometastases model.

Indexed as

3-D spheroidsAuger-electronsAutoradiographyDosimetryMC modellingRadiobiology/DosimetryRadionuclide TherapyTCP

Identifiers

PMID29959216
PMCPMC6330061
OpenAlexW2810406532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.