ArticleThe Journal of experimental medicine2018
A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses.
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Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
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- Ocrelizumab transiently alters microbiota and modulates immune response depending on treatment outcome.iScience · 2025Article
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- Follicle-like niches outside the cortex? 3D phase-contrast µCT revealed medullary B cell nodules in mucosa-draining lymph nodes.Frontiers in immunology · 2025Article
- A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses.Science immunology · 2024Article
- Microbiota and B-1 B cell repertoire development in mice.Current opinion in immunology · 2024Review
- T-betNature communications · 2024Article
- Dietary restriction mitigates the age-associated decline in mouse B cell receptor repertoire diversity.Cell reports · 2023Article
- Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism.Immunity · 2022Article
- Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts.Nature immunology · 2022Article
- Fate-mapping mice: new tools and technology for immune discovery.Trends in immunology · 2022Review
- B cell intrinsic and extrinsic factors impacting memory recall responses to SRBC challenge.Frontiers in immunology · 2022Article
- B cell fate mapping reveals their contribution to the memory immune response against helminths.Frontiers in immunology · 2022Article
- Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma.The Journal of experimental medicine · 2021Article
- IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns.Frontiers in immunology · 2021Article
- Rethinking mucosal antibody responses: IgM, IgG and IgD join IgA.Nature reviews. Immunology · 2020Review
- Article
- IgM memory B cells: specific effectors of innate-like and adaptive responses.Current opinion in immunology · 2020Review
- Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses.Cell reports · 2020Article
- Immunoglobulin M in Health and Diseases: How Far Have We Come and What Next?Frontiers in immunology · 2020Review
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 3 countries.
Simon Le GallouTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Zhicheng ZhouTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Lan-Huong ThaiTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Remi FritzenTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.ORCID 0000-0003-3457-8364
Alba Verge de Los AiresTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Jérôme MégretFlow Cytometry Core Facility, Structure Fédérative de Recherche Necker, Institut National de la Santé et de la Recherche Médicale US24-Centre National de la Recherche Scientifique UMS 3633, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Philipp YuInstitute of Immunology, Philipps-Universität Marburg, Marburg, Germany.
Daisuke KitamuraDivision of Molecular Biology, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.ORCID 0000-0002-5195-0474
Emmanuelle BilleTeam "Pathogeny of Systemic Infections", Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Fabiola TrosTeam "Pathogeny of Systemic Infections", Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Xavier NassifTeam "Pathogeny of Systemic Infections", Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Alain CharbitTeam "Pathogeny of Systemic Infections", Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.ORCID 0000-0001-5243-4861
Sandra WellerTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.ORCID 0000-0003-4725-2793
Jean-Claude WeillTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France jean-claude.weill@inserm.fr.
Claude-Agnès ReynaudTeam "Development of the Immune System," Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151-Centre National de la Recherche Scientifique UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France claude-agnes.reynaud@inserm.fr.ORCID 0000-0002-4519-4473
Délégation Paris 5 · FRPhilipps University of Marburg · DETokyo University of Science · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
To what extent immune responses against the gut flora are compartmentalized within mucosal tissues in homeostatic conditions remains a much-debated issue. We describe here, based on an inducible AID fate-mapping mouse model, that systemic memory B cell subsets, including mainly IgM
Indexed as
Immunity, MucosalImmunologic MemoryAgingAICDA (Activation-Induced Cytidine Deaminase)AnimalsAnti-Bacterial AgentsAntigens, CDBacterial ProteinsB-LymphocytesBone MarrowCytidine DeaminaseGastrointestinal MicrobiomeGerm-Free LifeGerminal CenterImmunizationImmunoglobulin AAICDA (Activation-Induced Cytidine Deaminase)Anti-Bacterial AgentsAntigens, CDBacterial ProteinsCytidine DeaminaseImmunoglobulin AImmunoglobulin MLuminescent Proteinssecretory IgMToll-Like Receptorsyellow fluorescent protein, Bacteria
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