Evidence map›Paper›PMID 29958463›Full record

ArticleInternational journal of molecular sciences2018

Exploring the Roles of

Nathan K P Wong, Helena Cheung, Emma L Solly, Laura Z Vanags, William Ritchie, Stephen J Nicholls, Martin K C Ng, Christina A Bursill, Joanne T M Tan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. New Perspectives on Cholesterol and Lipoprotein Metabolism.International journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Expression and Role of TRIM2 in Human Diseases.BioMed research international · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nathan K P WongImmunobiology Research Group, Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia. nathan.wong@sahmri.com.
Helena CheungImmunobiology Research Group, Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia. chelenacheung@gmail.com.
Emma L SollyHeart Health Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5000, Australia. emma.solly@sahmri.com.
Laura Z VanagsImmunobiology Research Group, Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia. laura.mcinnes3@gmail.com.
William RitchieDiscipline of Medicine, The University of Sydney School of Medicine, Camperdown, NSW 2006, Australia. william.ritchie@igh.cnrs.fr.
Stephen J NichollsHeart Health Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5000, Australia. stephen.nicholls@sahmri.com.
Martin K C NgDiscipline of Medicine, The University of Sydney School of Medicine, Camperdown, NSW 2006, Australia. mkcng@med.usyd.edu.au.
Christina A BursillImmunobiology Research Group, Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia. christina.bursill@sahmri.com.
Joanne T M TanImmunobiology Research Group, Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia. Joanne.Tan@sahmri.com.ORCID 0000-0003-1875-4882

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis, the process of forming new blood vessels, is crucial in the physiological response to ischemia, though it can be detrimental as part of inflammation and tumorigenesis. We have previously shown that high-density lipoproteins (HDL) modulate angiogenesis in a context-specific manner via distinct classical signalling pathways, enhancing hypoxia-induced angiogenesis while suppressing inflammatory-driven angiogenesis. Whether additional novel targets exist to account for these effects are unknown. A microarray approach identified two novel genes, cyclic-adenosine-monophosphate-response-element-binding protein 3 regulatory factor (

Indexed as

CarcinogenesisCell HypoxiaCell LineEndothelial CellsGene Expression RegulationGene Knockdown TechniquesHumansInflammationLipoproteins, HDLNeovascularization, PathologicNuclear ProteinsPhosphatidylcholinesRecombinant ProteinsTumor Suppressor Proteins1-palmitoyl-2-isolinoleoyl phosphatidylcholineCREB3 regulatory factor, humanLipoproteins, HDLNARF protein, humanNuclear ProteinsPhosphatidylcholinesRecombinant ProteinsTumor Suppressor ProteinsangiogenesisCREBRFhigh-density lipoproteinshypoxiainflammationTRIM2

Identifiers

PMID29958463
PMCPMC6073236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.