Evidence map›Paper›PMID 29957934›Full record

ArticleACS nano2018

Stereocomplex Prodrugs of Oligo(lactic acid)

Yu Tong Tam, Chengbin Huang, Michael Poellmann, Glen S Kwon

Abstract read
In one paragraph

Article in ACS nano, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. Crystallization of supersaturated PEG-b-PLA for the production of drug-loaded polymeric micelles.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  4. Improved Antitumor Efficiency ofInternational journal of nanomedicine · 2024
    Article
  5. Production of paclitaxel-loaded PEG-b-PLA micelles using PEG for drug loading and freeze-drying.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  6. Review
  7. Nanoparticulation of Prodrug into Medicines for Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  8. Article
  9. Review
  10. Oligo(Lactic Acid)Pharmaceutical research · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yu Tong TamPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin-Madison , 777 Highland Avenue , Madison , Wisconsin 53705-2222 , United States.ORCID 0000-0002-2661-5412
Chengbin HuangPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin-Madison , 777 Highland Avenue , Madison , Wisconsin 53705-2222 , United States.ORCID 0000-0002-0759-0942
Michael PoellmannPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin-Madison , 777 Highland Avenue , Madison , Wisconsin 53705-2222 , United States.ORCID 0000-0002-0085-3957
Glen S KwonPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin-Madison , 777 Highland Avenue , Madison , Wisconsin 53705-2222 , United States.ORCID 0000-0002-4798-652X
University of Wisconsin–Madison · US

Funding

Co-Delivery of Antifungal Agents: Toxicity and Efficacy in Invasive CandidiasisR01AI101157 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KWON, GLEN S. · 2013 to 2017
$1.9M
NIAID NIH HHS R01 AI101157
6 · The paper itself

Abstract

Herein we demonstrate the formation of stereocomplex prodrugs of oligo(l-lactic acid)

Indexed as

MicellesA549 CellsAnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationCell SurvivalDeoxycytidineDrug Screening Assays, AntitumorFemaleGemcitabineHumansLactatesLactic AcidMiceMice, NudeAntineoplastic AgentsDeoxycytidineGemcitabineLactatesLactic AcidMicellesPolyethylene Glycolspoly(lactic acid-ethylene glycol)Prodrugsbackbiting conversiongemcitabineoligo(lactic acid)n (o(LA)n)poly(ethylene glycol)-block-poly(d,l-lactic acid) (PEG-b-PLA)polymeric micellesprodrugstereocomplex

Identifiers

PMID29957934
PMCPMC6071312
OpenAlexW2811448579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.