Evidence map›Paper›PMID 29957829›Full record

Trial reportObesity (Silver Spring, Md.)2018

Racial Differences in Relative Skeletal Muscle Mass Loss During Diet-Induced Weight Loss in Women.

Gary R Hunter, David R Bryan, Juliano H Borges, M David Diggs, Stephen J Carter

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  6. Article
  7. Review
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gary R HunterDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
David R BryanDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Juliano H BorgesDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
M David DiggsDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Stephen J CarterDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Zevalin Radioimmunotherapy Using a Modified TreatmentM01RR000032 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICH, ROBERT R. · 1985 to 2008
$23.6M
UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2008 to 2011
$22.3M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
UAB Diabetes Research and Training CenterP60DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GARVEY, W TIMOTHY · 2008 to 2012
$8.4M
EXERCISE TRAINING IN OBESITY-PRONE BLACK AND WHITE WOMENR01DK049779 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOWER, BARBARA A, HUNTER, GARY R · 1995 to 2013
$4.4M
Frequency of aerobic/resistance training in older womenR01AG027084 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HUNTER, GARY R · 2005 to 2009
$1.6M
NCRR NIH HHS M01 RR000032NCRR NIH HHS UL1 RR025777NIA NIH HHS R01 AG027084NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS P60 DK079626NIDDK NIH HHS R01 DK049779
6 · The paper itself

Abstract

objectiveIt is unclear whether there are race-specific differences in the maintenance of skeletal muscle during energy restriction. Changes in relative skeletal muscle index (RSMI; limb lean tissue divided by height squared) were compared following (1) diet alone, (2) diet + aerobic training, or (3) diet + resistance training.

methodsOverweight, sedentary African American (AA; n = 72) and European American (EA; n = 68) women were provided an 800-kcal/d diet to reduce BMI < 25 kg/m

resultsAA women had greater RSMI and preserved RSMI during diet alone, while RSMI was significantly reduced among EA women (EA women -3.6% vs. AA women + 1.1%; P < 0.05). Diet + resistance training subjects retained RSMI (EA women + 0.2% vs. AA women + 1.4%; P = 50.05), whereas diet + aerobic training subjects decreased RSMI (EA women -1.4% vs. AA women -1.5%; P < 0.05). Maintenance of RSMI was related to delta walking ease and economy.

conclusionsCompared with AA women, EA women are less muscular and lose more muscle during weight loss without resistance training. During diet-induced weight loss, resistance training preserves skeletal muscle, especially among premenopausal EA women. Maintenance of muscle during weight loss associates with better ease and economy of walking.

Indexed as

Exercise TherapySarcopeniaAbsorptiometry, PhotonAdultBlack or African AmericanBody WeightDiet, ReducingExerciseFemaleHumansMuscle, SkeletalObesityOrgan SizeOverweightRacial GroupsResistance Training

Identifiers

PMID29957829
PMCPMC6107384
OpenAlexW2809759671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.