ReviewActa bio-medica : Atenei Parmensis2018
The complexity of loneliness.
Review in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
138 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Social Isolation and Loneliness Among Older Asian Immigrants Through the Lens of Sense of Coherence: Systematic Review of Qualitative Studies.Journal of advanced nursing · 2026Pooled it
- From verbal fluency to naturalistic speech: a scoping review of language correlates of loneliness and social isolation in older adults.Frontiers in aging neuroscience · 2026Pooled it
- Association of social isolation, loneliness and risk of cardiovascular diseases: Meta-analysis of cohort studies.BMC public health · 2025Pooled it
- The association between internet-use-disorder symptoms and loneliness: a systematic review and meta-analysis with a categorical approach.Psychological medicine · 2025Pooled it
- A Systematic Review and Correlational Meta-Analysis of Factors Associated With Resilience of Normally Aging, Community-Living Older Adults.The Gerontologist · 2022Pooled it
- The prevalence of loneliness across 113 countries: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2022Pooled it
- Assessing a facilitated social network intervention for health outcomes in lonely and socially isolated people: the pragmatic, cluster-randomized PALS trial.Frontiers in public health · 2026Trial
- Trial
- A 6-Week Program to Strengthen Resiliency Among Women With Metastatic Cancer: A Randomized Clinical Trial.The oncologist · 2023Trial
- Comparative effectiveness of two versions of a caring contacts intervention in healthcare providers, staff, and patients for reducing loneliness and mental distress: A randomized controlled trial.Journal of affective disorders · 2023Trial
- Symptom Clusters in Family Caregivers of Hematopoietic Stem Cell Transplantation Recipients: Loneliness as a Risk Factor.Transplantation and cellular therapy · 2023Trial
- The development and preliminary validation of a multidimensional assessment scale for loneliness in nursing homes.International journal of nursing studies advances · 2026Article
- The Applicability of Forest Therapy for Socially Isolated Young Adults: Parallel Changes in Psychological Distress and Mindfulness.International journal of environmental research and public health · 2026Article
- Measuring loneliness at a national scale: The measuring loneliness in England (INTERACT) study's approach and initial findings.BMC global and public health · 2026Article
- A Moderated Mediation Model Linking Speech-in-Noise Exposure, Speech Perception in Noise Ability, Loneliness, and Depression.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Whose Care Matters? The Protective Role of Perceived Care in the Long-Term Physical Health Consequences of Adolescent Loneliness.Journal of adolescence · 2026Article
- Loneliness in Chronic Obstructive Pulmonary Disease: A Multidimensional Determinant of Clinical Outcomes and Disease Management.Journal of clinical medicine · 2026Review
- Depression, anxiety, anger, and loneliness in older adults: comparing residential contexts and examining the role of loneliness.BMC geriatrics · 2026Article
- Loneliness Subtypes and Their Association With Prevalent and Incident Dementia.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Loneliness and emotional support helpline use in Spain: a 20-year observational study.Frontiers in psychology · 2026Article
78 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loneliness is a prevalent and global problem for adult populations, and a number of different studies have linked it to multiple chronic conditions, including: heart disease, lung disease, cardiovascular disease, hypertension, atherosclerosis, stroke, and metabolic disorders, such as obesity and metabolic disease. Is a major predictor of psychological problems, such as depression, psychological stress, and anxiety. Loneliness is linked to overall morbidity and mortality in adult populations. But limited interventions have demonstrated long-term effectiveness in reducing loneliness in adults with these same chronic conditions. Our research of the extant literature addresses the following question: What evidence exists regarding the relationships between loneliness and health? We focus on recent findings with respect to the links between loneliness and health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.