Evidence map›Paper›PMID 29957555›Full record

ArticlePsychiatry research2018

Exploring the pathophysiology of emotion-based impulsivity: The roles of the sympathetic nervous system and hostile reactivity.

Jessica R Peters, Tory A Eisenlohr-Moul, Erin C Walsh, Karen J Derefinko

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Jessica R PetersDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: jrpeters@gmail.com.
Tory A Eisenlohr-MoulDepartment of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.
Erin C WalshDepartment of Physical Medicine and Rehabilitation, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Karen J DerefinkoDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Brown University · USUniversity of Illinois Chicago · USUniversity of North Carolina at Chapel Hill · USUniversity of Tennessee Health Science Center · US

Funding

Training and Pilot CoreP50DA005312 · NIDA · UNIVERSITY OF KENTUCKY · PI LYNAM, DONALD R · 1987 to 2016
$19.5M
RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Postdoctoral Training in Reproductive Mood DisordersT32MH093315 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN Scott GIRDLER, David R. Rubinow · 2012 to 2026
$2.8M
Anger Rumination in the Development of PsychopathologyK23MH112889 · NIMH · BROWN UNIVERSITY · PI PETERS, JESSICA RACHAEL · 2018 to 2022
$966k
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachK99MH109667 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EISENLOHR-MOUL, TORY ANNE · 2016 to 2017
$164k
NIDA NIH HHS P50 DA005312NIMH NIH HHS K23 MH112889NIMH NIH HHS K99 MH109667NIMH NIH HHS T32 MH019927NIMH NIH HHS T32 MH093315
6 · The paper itself

Abstract

The tendency to engage in impulsive behavior in the context of negative affect, known as negative urgency, has emerged as a powerful transdiagnostic predictor of behavioral dysregulation. Although general vulnerability to negative affect (neuroticism) correlates with negative urgency, not all neurotic individuals engage in urgent behavior. Given prior experimental evidence that sympathetic nervous system (SNS) activation may promote emotion-related impulsivity, the present study examines tonic SNS activity as a moderator of the link between neuroticism and negative urgency. Participants (N = 194) completed measures of neuroticism and negative urgency, as well as a stress task. They also underwent assessment of tonic SNS activity (cardiac pre-ejection period). The link between neuroticism and negative urgency was strengthened for individuals with higher tonic SNS activity; however, this was not the case for behavioral performance on the task. A similar pattern was demonstrated for hostile reactivity to the stress task; increased hostile response partially explained the interaction between SNS activation and neuroticism on negative urgency. These findings suggest a potential facilitative role of the SNS in hostile reactivity and emotion-driven impulsivity among more neurotic individuals.

Indexed as

HostilityAdultAnxiety DisordersEmotionsFemaleHumansImpulsive BehaviorLongitudinal StudiesMaleNeuroticismStudentsSympathetic Nervous SystemYoung AdultAngerImpulsivityNegative urgencyNeuroticismPre-ejection periodShame

Identifiers

PMID29957555
PMCPMC6309543
OpenAlexW2808921590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.