ArticleAmerican journal of men's health2018
Depression and Prostate Cancer: Examining Comorbidity and Male-Specific Symptoms.
Article in American journal of men's health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of risk factors associated with depression and anxiety in cancer patients.PloS one · 2024Pooled it
- The effectiveness of psychological intervention for depression, anxiety, and distress in prostate cancer: a systematic review of literature.Prostate cancer and prostatic diseases · 2021Pooled it
- Assessing the Impact of the Prostate Cancer Patient Empowerment Program (PC-PEP) on Relationship Satisfaction, Quality of Life, and Support Group Participation: A Randomized Clinical Trial.Current oncology (Toronto, Ont.) · 2024Trial
- High Frequency of Depression in Advanced Cancer with Concomitant Comorbidities: A Registry Study.Cancers · 2025Article
- Prostate cancer biomarkers: from early diagnosis to precision treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024Review
- Article
- Impact of SARS-CoV-2 on Host Factors Involved in Mental Disorders.Frontiers in microbiology · 2022Review
- Men's Psychotherapy Use, Male Role Norms, and Male-Typical Depression Symptoms: Examining 716 Men and Women Experiencing Psychological Distress.Behavioral sciences (Basel, Switzerland) · 2021Article
- Gender Differences in Psychosocial, Religious, and Spiritual Aspects in Coping: A Cross-Sectional Study with Cancer Patients.Women's health reports (New Rochelle, N.Y.) · 2021Article
- Circulating Inflammation Markers Partly Explain the Link Between the Dietary Inflammatory Index and Depressive Symptoms.Journal of inflammation research · 2021Article
- Baseline patient reported outcomes data shows high prevalence of overactive bladder, sexual dysfunction, depression and anxiety in Canadian men with newly diagnosed localized prostate cancer.Translational andrology and urology · 2020Article
- Promoting integrated care in prostate cancer through online prostate cancer-specific holistic needs assessment: a feasibility study in primary care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Suicidal Ideation in Newly-Diagnosed Chinese Cancer Patients.Frontiers in psychiatry · 2020Article
- The Cost of Bottling It Up: Emotion Suppression as a Mediator in the Relationship Between Anger and Depression Among Men with Prostate Cancer.Cancer management and research · 2020Article
- Association of Monoamine Oxidase A with Tumor Burden and Castration Resistance in Prostate Cancer.Current therapeutic research, clinical and experimental · 2020Article
- Current Mental Distress Among Men With a History of Radical Prostatectomy and Related Adverse Correlates.American journal of men's healthArticle
- The Effect of Multimorbidity Patterns and the Impact of Comorbid Anxiety and Depression on Primary Health Service Use: The Men Androgen Inflammation Lifestyle Environment and Stress (MAILES) Study.American journal of men's healthArticle
- The Anxiety Depression Pathway Among Men Following a Prostate Cancer Diagnosis: Cross-Sectional Interactions Between Anger Responses and Loneliness.American journal of men's healthArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Depression in men with prostate cancer is a significant and complex issue that can challenge clinicians' diagnostic efforts. The objective of the current study was to evaluate prototypic and male-specific depression symptoms and suicidal ideation in men with a diagnosis of prostate cancer relative to those with and without comorbidity. The Patient Health Questionnaire-9 (PHQ-9) and Male Depression Risk Scale-22 (MDRS-22) were completed online along with demographic and background variables by 100 men with a diagnosis of prostate cancer ( n = 54 prostatectomy, n = 33 receiving active treatment). Hierarchical logistic regression was used to examine recent (past 2 weeks) suicide ideation. Over one-third of the sample (38%) reported a comorbidity, and this group had significantly higher total depression scores on the PHQ-9 (Cohen's d = 0.65), MDRS-22 emotion suppression ( d = 0.35), and drug use subscales ( d = 0.38) compared to respondents without comorbidity. A total of 14% reported recent suicidal ideation, of which 71.4% of cases were identified by the PHQ-9 "moderate" cut-off, and 85.7% of cases were identified by the MDRS-22 "elevated" cut-off. After control variables, MDRS-22 subscales accounted for 45.1% of variance in recent suicidal ideation. While limited by the exclusive use of self-report data, findings point to the potential benefits of evaluating male-specific symptoms as part of depression and suicide risk screening in men with prostate cancer and the need to be mindful of the heightened risk for depression among men with prostate cancer who have comorbidity.
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