Observational studyCommunity dentistry and oral epidemiology2018
Tooth loss is a complex measure of oral disease: Determinants and methodological considerations.
Observational study in Community dentistry and oral epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Associations of oral health with colorectal cancer risk: accumulated evidences from observational studies.BMC cancer · 2026Pooled it
- The Effect of Tobacco Smoking on Tooth Loss: A Systematic Review and Meta-Analysis.Journal of clinical periodontology · 2026Pooled it
- Association of tooth loss and nutritional status in adults: an overview of systematic reviews.BMC oral health · 2024Pooled it
- Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.Nature communications · 2019Pooled it
- Interpreting Population Survey Measures of Periodontal Disease Experience Under Severity-Dependent Tooth Loss.Journal of clinical periodontology · 2026Article
- Number of Teeth and Posterior Occlusal Pairs by Sociodemographic Factors in the Finnish Adult Population, Results From the Healthy Finland 2023 Study.Journal of oral rehabilitation · 2026Article
- Tooth extractions and the prevalence of postoperative complications in individuals with and without diabetes: a retrospective cross-sectional study.BMC oral health · 2026Article
- Prosthetic complications of implant-supported overdentures: a retrospective study on the influence of attachment type and implant number.BMC research notes · 2026Article
- Impact of a removable prosthesis on chewing ability, quality of life, and patient satisfaction.Scientific reports · 2025Article
- The Impact of Oral Health and Dental Services on the Prevalence of Subjective Cognitive Decline Among Middle-Aged and Older US Adults: Behavioral Risk Factor Surveillance System, 2022.Preventing chronic disease · 2025Article
- Association of tooth loss with circadian syndrome in US adults: the mediated role of systemic inflammation.Clinical oral investigations · 2025Article
- Association of participant reported oral health, tooth loss, interdental cleaning and dental visits with serum CRP.Scientific reports · 2025Article
- Impact of smoking on cost-effectiveness of 10-48 years of periodontal care.Periodontology 2000 · 2025Review
- A visualization system for intelligent diagnosis and statistical analysis of oral diseases based on panoramic radiography.Scientific reports · 2025Article
- Association between tooth loss and geriatric syndromes in older adults: a cohort study from a rural area in eastern China.Aging clinical and experimental research · 2025Article
- Tooth wear and tertiary crowding: a 13-year cohort study in Amazon Indigenous populations.Progress in orthodontics · 2025Article
- Multimorbidity and tooth loss: data from Chilean National Health Survey 2016-2017.BMC oral health · 2024Article
- Exploring lived experiences with tooth loss among fully edentulous patients attending Makerere University Dental Hospital, Kampala, Uganda.BMC oral health · 2024Article
- Article
- Association between dental diseases and stroke.The Saudi dental journal · 2024Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
objectivesCounts of missing teeth or measures of incident tooth loss are gaining attention as a simple way to measure dental status in large population studies. We explore the meaning of these metrics and how missing teeth might influence other measures of dental status.
methodsAn observational study was performed in 2 contrasting adult populations. In total, 62 522 adult participants were available with clinically assessed caries and periodontal indices from the Swedish arm of the Gene-Lifestyle Interactions and Dental Endpoints Study (GLIDE) and the Korea National Health and Nutrition Examination Survey (KNHANES) in the Republic of Korea. Longitudinal measures of tooth loss were available for 28 244 participants in GLIDE with median follow-up of 10.6 years.
resultsIn longitudinal analysis, hazard for tooth loss was associated with baseline dental status (previous tooth loss, periodontal status and caries status) and socio-demographic variables (age, smoking status and highest educational level). Analysis of cross-sectional data suggested that indices of caries exposure were not independent of periodontal status. The strength and direction of association varied between groups, even for measures specifically intended to avoid measuring tooth loss. Individuals with impaired periodontal health (community periodontal index [CPI] 3 or higher in any sextant) had higher standardized decayed and filled surfaces (DFS; number of DFS divided by total number of tooth surfaces) in GLIDE (incidence risk ratio [IRR] 1.05 [95% CI: 1.04, 1.07], but lower standardized DFS in KNHANES (IRR: 0.95 [0.92, 0.98]) than individuals with better periodontal health (CPI <3 in all sextants).
conclusionsIncident tooth loss is a complex measure of dental disease, with multiple determinants. The relative importance of dental caries and periodontal disease as drivers of tooth loss differs between age groups. Measures of dental caries exposure are associated with periodontal status in the studied populations, and these associations can be population-specific. Consideration of the study-specific properties of these metrics may be required for valid inference in large population studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.