Evidence map›Paper›PMID 29956586›Full record

ArticleMolecular pain

Nonmuscle myosin II isoforms interact with sodium channel alpha subunits.

Bhagirathi Dash, Chongyang Han, Stephen G Waxman, Sulayman D Dib-Hajj

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Trafficking mechanisms underlying NaChannels (Austin, Tex.) · 2020
    Review
  4. Article
  5. Immortalized Dorsal Root Ganglion Neuron Cell Lines.Frontiers in cellular neuroscience · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bhagirathi Dash1 Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5314-5372
Chongyang Han1 Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Stephen G Waxman1 Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Sulayman D Dib-Hajj1 Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium channels play pivotal roles in health and diseases due to their ability to control cellular excitability. The pore-forming α-subunits (sodium channel alpha subunits) of the voltage-sensitive channels (i.e., Na

Indexed as

Action PotentialsAnimalsAnkyrinsBrainCell Line, TransformedElectric StimulationGanglia, SpinalGene Expression RegulationGreen Fluorescent ProteinsHumansImmunoprecipitationMiceMice, Inbred C57BLMice, TransgenicMolecular Motor ProteinsMyosin Heavy ChainsAnkyrinsGreen Fluorescent ProteinsMolecular Motor ProteinsMYH9 protein, humanMyosin Heavy ChainsNAV1.6 Voltage-Gated Sodium ChannelNonmuscle Myosin Type IIBnonmuscle myosin type IIB heavy chainSCN8A protein, humanmyh10myh9Myosinsnonmuscle myosin heavy chainssodium channelvoltage clamp

Identifiers

PMID29956586
PMCPMC6052497
OpenAlexW2810957066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.