Evidence map›Paper›PMID 29956580›Full record

ReviewExpert review of gastroenterology & hepatology2018

Treating pancreatic cancer: more antioxidants more problems?

Matthew S Alexander, Joseph J Cullen

Abstract readEditorialReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Expert review of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew S Alexandera Departments of Surgery and Radiation Oncology, Holden Comprehensive Cancer Center , The University of Iowa Hospitals and Clinics and the University of Iowa College of Medicine , Iowa City , IA , USA.
Joseph J Cullena Departments of Surgery and Radiation Oncology, Holden Comprehensive Cancer Center , The University of Iowa Hospitals and Clinics and the University of Iowa College of Medicine , Iowa City , IA , USA.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Project 3: MRI Imaging of Redox Active Fe Predicts GBM Responses to Pharmacological AscorbateP01CA217797 · NCI · UNIVERSITY OF IOWA · PI BUETTNER, GARRY R · 2018 to 2022
$9.6M
University of Iowa Surgical Oncology Training GrantT32CA148062 · NCI · UNIVERSITY OF IOWA · PI WEIGEL, RONALD J · 2010 to 2020
$3.8M
Pharmacological Ascorbate as a Radiosensitizer in Pancreatic CancerR01CA184051 · NCI · UNIVERSITY OF IOWA · PI CULLEN, JOSEPH J · 2015 to 2018
$1.4M
Role of HIF-1 alpha in EcSOD-Induced Growth Inhibition of Pancreatic CancerI01BX001318 · VA · IOWA CITY VA MEDICAL CENTER · PI CULLEN, JOSEPH J · 2013 to 2018
–
BLRD VA I01 BX001318NCI NIH HHS P01 CA217797NCI NIH HHS R01 CA184051NCI NIH HHS T32 CA148062
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dietary SupplementsOxidative StressAntineoplastic AgentsAntioxidantsCarcinoma, Pancreatic DuctalGenetic TherapyGlutathione PeroxidaseHumansMolecular Targeted TherapyNF-E2-Related Factor 2Oxidation-ReductionPancreatic NeoplasmsSignal TransductionSuperoxide DismutaseTreatment OutcomeAntineoplastic AgentsAntioxidantsGlutathione PeroxidaseNFE2L2 protein, humanNF-E2-Related Factor 2Superoxide Dismutase

Identifiers

PMID29956580
PMCPMC6317716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.