Evidence map›Paper›PMID 29956468›Full record

ReviewInternational wound journal2018

Lipoedema is not lymphoedema: A review of current literature.

Eran Shavit, Uwe Wollina, Afsaneh Alavi

2 registry-linked trialsOpen access · greenAbstract readComparative StudyReview
In one paragraph

Review in International wound journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05329324 completednot on this mapstarted 2022, after this paper: background citation

Evaluation of Neuropathic Pain in Lipedema

TypeobservationalSponsorDokuz Eylul UniversityRan2022 to 2023Enrolled85ConditionsLipedemaArmsQuestionnaire for study group, Questionnaire for control group
NCT07061808 completednot on this mapstarted 2022, after this paper: background citation

The Reliability and Validity of the Turkish Version of the Lipedema Screening Questionnaire

TypeobservationalSponsorGazi UniversityRan2022 to 2023Enrolled59ConditionsLipedema, WomenArmsLipedema Screening Questionnaire
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. [Differential diagnostics of lipedema and lymphedema : A practical guideline].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018
    Guideline
  4. Guideline
  5. Trial
  6. Review
  7. Review
  8. Article
  9. Review
  10. Lipedema Reduction Surgery Outcomes and Comorbidities: A Retrospective Study.Plastic and reconstructive surgery. Global open · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Hybrid approach of massive lipolymphedema of the thigh: A novel surgical technique.Journal of vascular surgery. Venous and lymphatic disorders · 2025
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Eran ShavitDivision of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-2397-6316
Uwe WollinaDepartment of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
Afsaneh AlaviDivision of Dermatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
University of Toronto · CAStädtisches Klinikum Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipoedema is a rare painful disorder of the adipose tissue. It essentially affects females and is often misdiagnosed as lymphoedema or obesity. It is globally misdiagnosed or underdiagnosed, and the literature is lacking appropriate guidance to assist clinicians towards this diagnosis. However, the need to recognise this disorder as a unique entity has important implications to establish proper treatment and, therefore, its tremendous effect on patients. Early diagnosis and treatment can turn these patients' lives upside down. The aim of this review is to focus on the clinical guidance, differential diagnosis, and management strategies. In addition, other aspects of lipoedema, including epidemiology and pathogenesis, are also being discussed here. Lipoedema is distinct from obesity and distinct from lymphoedema, although it might progress to involve the venous and lymphatic system (venolipedema or lympholipedema or both). Late diagnosis can leave the patient debilitated. Management of lipoedema includes weight loss, control of oedema, complex decongestive physiotherapy, liposuction, and laser-assisted lipolysis. However; there are increasing reports on tumescent liposuction as the preferred surgical option with long-lasting results. The role of more randomised controlled studies to further explore the management of this clinical entity remains promising.

Indexed as

Diagnostic ErrorsFemaleHumansLipedemaLymphedemaMalelipoedemalymphoedemalympholipedema (in German lipo-lymphedema)tumescent liposuction

Identifiers

PMID29956468
PMCPMC7949771
OpenAlexW2810626326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.