Evidence map›Paper›PMID 29956403›Full record

ArticleHuman brain mapping2018

Increased fMRI activity correlations in autobiographical memory versus resting states.

Kristen N Warren, Molly S Hermiller, Aneesha S Nilakantan, Jonathan O'Neil, Robert T Palumbo, Joel L Voss

Abstract readComparative Study
In one paragraph

Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristen N WarrenDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-6960-8466
Molly S HermillerDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Aneesha S NilakantanDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Jonathan O'NeilDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Robert T PalumboDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Joel L VossDepartment of Medical Social Sciences and Interdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Funding

TRAINING PROGRAM IN THE NEUROSCIENCE OF HUMAN COGNITIONT32NS047987 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rodrigo M Braga, Christina Maria Zelano · 2006 to 2026
$5.6M
SYNAPTIC SUBSTRATES OF AGE-DEPENDENT MEMORY DEFICITSR01AG017139 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DISTERHOFT, JOHN F · 1999 to 2013
$4.6M
Noninvasive Manipulation of Hippocampal-Cortical Brain Networks and MemoryR01MH106512 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI VOSS, JOEL L · 2015 to 2019
$2.7M
NIA NIH HHS R01 AG017139NIMH NIH HHS R01 MH106512NINDS NIH HHS T32 NS047987
6 · The paper itself

Abstract

Autobiographical memory retrieval is associated with activity of a distributed network that is similar to the default-mode network (DMN) identified via activity correlations measured during rest. We tested whether activity correlations could be used to identify the autobiographical network during extended bouts of retrieval. Global-correlativity analysis identified regions with activity correlation differences between autobiographical-retrieval and resting states. Increased correlations were identified for retrieval versus resting states within a distributed network that included regions prototypical for autobiographical memory. This network segregated into two subnetworks comprised of regions related to memory versus cognitive control, suggesting greater functional segregation during autobiographical retrieval than rest. DMN regions were important drivers of these effects, with increased correlations between DMN and non-DMN regions and segregation of the DMN into distinct subnetworks during retrieval. Thus, the autobiographical network can be robustly identified via activity correlations and retrieval is associated with network functional organization distinct from rest.

Indexed as

Magnetic Resonance ImagingMemory, EpisodicAdolescentAdultBrainBrain MappingFemaleHumansMaleMental RecallNeural PathwaysRestYoung Adultautobiographical memorybrain networksdefault-mode networkfMRI connectivityresting state

Identifiers

PMID29956403
PMCPMC6314301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.