Evidence map›Paper›PMID 29956393›Full record

ArticlePsycho-oncology2018

Suicide rates among patients with cancers of the digestive system.

Chelsea Anderson, Eliza M Park, Donald L Rosenstein, Hazel B Nichols

Abstract read
In one paragraph

Article in Psycho-oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review on factors associated with self-perceived burden among cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  9. Colorectal Cancer and the Risk of Mortality Among Individuals with Suicidal Ideation.International journal of environmental research and public health · 2025
    Article
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  19. Health-Related Quality of Life among Cancer Survivors Depending on the Occupational Status.International journal of environmental research and public health · 2021
    Article
  20. Risk factors associated with suicide among hepatocellular carcinoma patients: A surveillance, epidemiology, and end results analysis.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chelsea AndersonDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0001-6535-481X
Eliza M ParkDepartment of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-2848-4989
Donald L RosensteinDepartment of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA.
Hazel B NicholsDepartment of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA.

Funding

Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
A Psychosocial Intervention to Improve Outcomes for Parents with Advanced CancerK07CA218167 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARK, ELIZA MYUNG · 2017 to 2021
$884k
NCI NIH HHS K07 CA218167NCI NIH HHS T32 CA057726
6 · The paper itself

Abstract

objectivePrevious studies have suggested that suicide rates are elevated among cancer patients relative to the general population. In this analysis, we comprehensively evaluated characteristics associated with higher suicide rates among patients with cancers of the digestive system.

methodsUsing the United States Surveillance, Epidemiology, and End Results database, we identified all patients diagnosed with digestive system cancers during 2000 to 2014. Patients were classified as having died of suicide if their cause of death in Surveillance, Epidemiology, and End Results was listed as "suicide and self-inflicted injury." Suicide rates were compared to age-, sex-, and race-adjusted rates in the general population.

resultsA total of 881 suicides were identified among 856 293 patients diagnosed with digestive system cancers. The suicide rate in this population was 32.8 per 100 000 person-years and was nearly twice that in the general population (standardized mortality ratio [SMR] = 1.91; 95% CI, 1.79-2.04). Suicide rates were significantly elevated for all cancer sites but were highest for esophageal (SMR = 5.03), pancreatic (SMR = 5.28), stomach (SMR = 2.84), and liver (SMR = 2.14) cancers. Standardized mortality ratios for suicide were highest within the first 5 years of diagnosis and increased with age at diagnosis for all sites except colon and stomach.

conclusionsPatients with cancers of the digestive system have a higher incidence of suicide than the general population. Suicide rates among esophageal and pancreatic cancer patients are more than 5 times general population rates. The involvement of psychiatrists and other mental health professionals may be a critical component of cancer care for these high-risk patient subgroups.

Indexed as

AdultAgedAge DistributionCause of DeathDigestive System NeoplasmsFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsSEER ProgramSuicideUnited Statescanceresophageal cancerliver canceroncologypancreatic cancersuicide

Identifiers

PMID29956393
PMCPMC6584762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.