Evidence map›Paper›PMID 29956263›Full record

ReviewNeurology and therapy2018

Monitoring Progressive Multiple Sclerosis with Novel Imaging Techniques.

Maria Petracca, Monica Margoni, Giulia Bommarito, Matilde Inglese

Open access · goldAbstract readReview
In one paragraph

Review in Neurology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Periventricular gradient of TNeuroImage. Clinical · 2022
    Article
  4. Review
  5. A Milestone in Multiple Sclerosis Therapy: Monoclonal Antibodies Against CD20-Yet Progress Continues.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  6. Deciphering Multiple Sclerosis Progression.Frontiers in neurology · 2021
    Review
  7. Article
  8. Advances in brain imaging in multiple sclerosis.Therapeutic advances in neurological disorders · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Maria PetraccaDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Monica MargoniDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Giulia BommaritoDepartment of Neuroscience, Rehabilitation, Genetics and Maternal and Perinatal Sciences, University of Genoa, Genoa, Italy.
Matilde IngleseDepartment of Neuroscience, Rehabilitation, Genetics and Maternal and Perinatal Sciences, University of Genoa, Genoa, Italy. matilde.inglese@mssm.edu.
Icahn School of Medicine at Mount Sinai · USUniversity of Genoa · IT

Funding

National Multiple Sclerosis Society NMSS RG 5120A3/1
6 · The paper itself

Abstract

Imaging markers for monitoring disease progression in progressive multiple sclerosis (PMS) are scarce, thereby limiting the possibility to monitor disease evolution and to test effective treatments in clinical trials. Advanced imaging techniques that have the advantage of metrics with increased sensitivity to short-term tissue changes and increased specificity to the structural abnormalities characteristic of PMS have recently been applied in clinical trials of PMS. In this review, we (1) provide an overview of the pathological features of PMS, (2) summarize the findings of research and clinical trials conducted in PMS which have applied conventional and advanced magnetic resonance imaging techniques and (3) discuss recent advancements and future perspectives in monitoring PMS with imaging techniques.

Indexed as

Advanced imagingBiomarkerClinical trialsProgressive multiple sclerosis

Identifiers

PMID29956263
PMCPMC6283788
OpenAlexW2809802875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.