Evidence map›Paper›PMID 29956116›Full record

Observational studyAIDS and behavior2019

The Role of Religious Service Attendance, Psychosocial and Behavioral Determinants of Antiretroviral Therapy (ART) Adherence: Results from HPTN 063 Cohort Study.

Yusuf Ransome, Kenneth H Mayer, Kiyomi Tsuyuki, Matthew J Mimiaga, Carlos E Rodriguez-Diaz, Kriengkrai Srithanaviboonchai, Ruth K Friedman, Mohammed Limbada, Steven A Safren, HIV Prevention Trials Network 063 Team

Abstract readObservational Study
In one paragraph

Observational study in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusuf RansomeDepartment of Social and Behavioral Sciences, Yale School of Public Health, 60 College Street, LEPH 4th Floor, New Haven, CT, 06510, USA. yusuf.ransome@yale.edu.ORCID http://orcid.org/0000-0003-4170-2001
Kenneth H MayerThe Fenway Institute, Fenway Health, Boston, MA, USA.
Kiyomi TsuyukiDivision of Global Public Health, School of Medicine, University of San Diego, San Diego, CA, USA.
Matthew J MimiagaDepartment of Social and Behavioral Sciences, Brown University School of Public Health, Providence, RI, USA.
Carlos E Rodriguez-DiazUniversity of Puerto Rico School of Public Health, San Juan, PR, USA.
Kriengkrai SrithanaviboonchaiFaculty of Medicine, and Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Ruth K FriedmanInstituto de Pesquisa Clinica Evandro Chagas, Rio de Janeiro, Brazil.
Mohammed LimbadaZambart, Lusaka, Zambia.
Steven A SafrenDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
HIV Prevention Trials Network 063 Team

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
University of Puerto Rico Mentoring Institute for HIV Mental Health ResearchR25MH083617 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ZORRILLA, CARMEN D · 2008 to 2020
$3.7M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
SALUD: Syndemic Alcohol Use Disorders, Violence, and HIV/STI in Young Latino MenK01AA025009 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TSUYUKI, KIYOMI · 2017 to 2021
$939k
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Social Capital and Late HIV Diagnosis in the United StatesK01MH111374 · NIMH · YALE UNIVERSITY · PI RANSOME, YUSUF · 2017 to 2021
$749k
National Institute of Mental Health K01MH111374National Institute on Alcohol Abuse and Alcoholism K01AA025009National Institute on Drug Abuse 9K24DA040489NIAAA NIH HHS K01 AA025009NIAID NIH HHS UM1 AI068619NIDA NIH HHS K24 DA040489NIMH, NIAID, NIDA UM1 A1068619NIMH NIH HHS K01 MH111374NIMH NIH HHS R25 MH083617NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Early and sustained antiretroviral therapy (ART) adherence can suppress the HIV virus in individuals and reduce onward transmission of HIV in the population. Religiosity has been associated with better HIV clinical outcomes. Data are from a longitudinal, observational study of 749 HIV-infected individuals from Brazil, Zambia, and Thailand (HPTN 063). Ordered logistic regression assessed whether religious service attendance was associated with ART adherence (self-reported and plasma HIV-RNA) and moderated the association between alcohol problems and ART adherence. In each country, > 80% of participants reported high self-reported ART adherence (good/very good/excellent). Religious service attendance exceeded 85% but was statistically unrelated to adherence. In combined-country models, (p = 0.03) as alcohol problems increased, the probability of high self-reported ART adherence, as well as viral-load, became weaker at higher compared to low service attendance frequency. Future studies should evaluate spirituality variables and replicate the moderation analyses between religious attendance and alcohol problems.

Indexed as

Medication AdherenceReligionSocial SupportAdolescentAdultAlcohol-Related DisordersAnti-Retroviral AgentsBrazilCohort StudiesFemaleHIV InfectionsHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedAnti-Retroviral AgentsRNA, ViralAlcoholAntiretroviral therapy (ART) adherenceHIV/AIDSHPTNReligion

Identifiers

PMID29956116
PMCPMC6310676

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.