Evidence map›Paper›PMID 29956081›Full record

ArticleCell biochemistry and biophysics2018

p47phox-Dependent Reactive Oxygen Species Stimulate Nuclear Translocation of the FoxO1 Transcription Factor During Metabolic Inhibition in Cardiomyoblasts.

Ellis N Ter Horst, Nynke E Hahn, Dirk Geerts, René J P Musters, Walter J Paulus, Albert C van Rossum, Christof Meischl, Jan J Piek, Hans W M Niessen, Paul A J Krijnen

Open access · hybridAbstract read
In one paragraph

Article in Cell biochemistry and biophysics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ellis N Ter HorstDepartment of Cardiology, Amsterdam UMC, location AMC, Amsterdam, The Netherlands. e.terhorst@vumc.nl.ORCID http://orcid.org/0000-0002-3721-565X
Nynke E HahnAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Dirk GeertsDepartment of Medical Biology L2-109, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
René J P MustersAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Walter J PaulusAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Albert C van RossumAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Christof MeischlAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Jan J PiekDepartment of Cardiology, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Hans W M NiessenAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Paul A J KrijnenAmsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLNetherlands Heart Institute · NL

Funding

Institute for cardiovascular research 2008V076Netherlands Heart Institute 140.01
6 · The paper itself

Abstract

Reactive oxygen species (ROS) control forkhead box O (FOXO) transcription factor activity by influencing their nuclear translocation. However, knowledge of the ROS cellular source(s) involved herein remains scarce. Recently, we have shown p47

Indexed as

AnimalsCell LineCell NucleusCulture MediaCytosolForkhead Box Protein O1Microscopy, FluorescenceMyocytes, CardiacNADPH OxidasesNerve Tissue ProteinsRatsReactive Oxygen SpeciesRNA InterferenceRNA, Small InterferingTyrosine3-nitrotyrosineCulture MediaForkhead Box Protein O1Foxo1 protein, ratNADPH OxidasesNerve Tissue Proteinsneutrophil cytosolic factor 1Reactive Oxygen SpeciesRNA, Small InterferingTyrosineFOXO1IschemiaNADPH oxidasep47phoxReactive oxygen species

Identifiers

PMID29956081
PMCPMC6097050
OpenAlexW2810227432

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.