Evidence map›Paper›PMID 29956078›Full record

ArticleJournal of clinical immunology2018

Severe Congenital Neutropenia associated with SRP54 mutation in 22q11.2 Deletion Syndrome: Hematopoietic Stem Cell Transplantation Results in Correction of Neutropenia with Adequate Immune Reconstitution.

Marcus A Carden, James A Connelly, Elizabeth P Weinzierl, Lisa J Kobrynski, Shanmuganathan Chandrakasan

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Human SRP Subunits Coordinate Protein Targeting and mRNA Quality Control.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marcus A CardenAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, 2015 Uppergate Drive, ECC Room 418, Atlanta, GA, 30030, USA.ORCID 0000-0003-3860-3619
James A ConnellyDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Elizabeth P WeinzierlDepartment of Pathology, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Lisa J KobrynskiDepartment of Allergy and Immunology, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.
Shanmuganathan ChandrakasanAflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, 2015 Uppergate Drive, ECC Room 418, Atlanta, GA, 30030, USA. shanmuganathan.chandrakasan@emory.edu.
Emory University · USChildren's Healthcare of Atlanta · USVanderbilt University Medical Center · US

Funding

Atlanta Pediatric Scholars ProgramK12HD072245 · NICHD · EMORY UNIVERSITY · PI Shari Barkin · 2012 to 2026
$5.5M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseMutationBiomarkersBiopsyBone MarrowDiGeorge SyndromeGenetic Association StudiesHematopoietic Stem Cell TransplantationHumansImmune ReconstitutionImmunophenotypingInfant, NewbornMaleNeutropeniaNeutrophilsPhenotypeBiomarkersSignal Recognition ParticleSRP54 protein, human

Identifiers

PMID29956078
OpenAlexW2810784089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.