Evidence map›Paper›PMID 29955973›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2018

Regional alterations of cerebral [

Nick Van Laeken, Glenn Pauwelyn, Robrecht Dockx, Benedicte Descamps, Boudewijn Brans, Kathelijne Peremans, Chris Baeken, Ingeborg Goethals, Christian Vanhove, Filip De Vos

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. [Translational psychiatry · 2025
    Article
  2. PET imaging of animal models with depressive-like phenotypes.European journal of nuclear medicine and molecular imaging · 2023
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nick Van LaekenLaboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Glenn PauwelynLaboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium. glenn.pauwelyn@Ugent.be.
Robrecht DockxFaculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
Benedicte DescampsInstitute Biomedical Technology - Medisip - Infinity, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium.
Boudewijn BransDepartment of Radiology and Nuclear Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Kathelijne PeremansFaculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
Chris BaekenDepartment of Psychiatry and Medical Psychology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Ingeborg GoethalsDepartment of Radiology and Nuclear Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Christian VanhoveInstitute Biomedical Technology - Medisip - Infinity, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium.
Filip De VosLaboratory of Radiopharmacy, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preclinical research has been indispensable in the exploration of the neurological basis of major depressive disorder (MDD). The present study aimed to examine effects on regional brain activity of two frequently used depression models, the chronic unpredictable mild stress (CUMS)- and the chronic corticosterone (CORT) depression model. The CUMS and CORT depression model were induced by exposing male Long-Evans rats to a 4-week procedure of unpredictable mild stressors or a 3-week procedure of chronic corticosterone, respectively. Positron emission tomography with [

Indexed as

Positron-Emission TomographyStress, PsychologicalAnimalsAnxietyBrainChronic DiseaseCorticosteroneDepressionDisease Models, AnimalFluorine RadioisotopesFluorodeoxyglucose F18GlucoseImmobility Response, TonicMaleMotor ActivityNeuroimagingCorticosteroneFluorine-18Fluorine RadioisotopesFluorodeoxyglucose F18GlucoseRadiopharmaceuticals[18F]FDGCerebral glucose metabolismChronic unpredictable mild stressCorticosteroneDepressionLong–Evans rats

Identifiers

PMID29955973
OpenAlexW2810928286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.