Evidence map›Paper›PMID 29955971›Full record

ArticleParasitology research2018

Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil.

Soumaya Hajaji, Ines Sifaoui, Atteneri López-Arencibia, María Reyes-Batlle, Ignacio A Jiménez, Isabel L Bazzocchi, Basilio Valladares, Hafidh Akkari, Jacob Lorenzo-Morales, José E Piñero

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effect of essential oils onParasitology · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Evaluation of the therapeutic efficacy of some essential oils in experimentally immunosuppressed mice infected withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  8. Chemistry and Bioactivity ofMolecules (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. A Comprehensive Study of Therapeutic Applications of Chamomile.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  13. Chamomile (Life (Basel, Switzerland) · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Soumaya HajajiLaboratoire de Parasitologie, École Nationale de Médecine Vétérinaire de Sidi Thabet, Université de la Manouba, 2020, Manouba, Tunisie. soumayahajjaji86@gmail.com.
Ines SifaouiLaboratoire Matériaux-Molécules et Applications, IPEST, University of Carthage, La Marsa, Tunisia.
Atteneri López-ArencibiaUniversity Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, La Laguna, Tenerife, Canary Islands, Spain.
María Reyes-BatlleUniversity Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, La Laguna, Tenerife, Canary Islands, Spain.
Ignacio A JiménezInstituto Universitario de Bio-Orgánica Antonio González, Departamento Química Orgánica, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
Isabel L BazzocchiInstituto Universitario de Bio-Orgánica Antonio González, Departamento Química Orgánica, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
Basilio ValladaresUniversity Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, La Laguna, Tenerife, Canary Islands, Spain.
Hafidh AkkariLaboratoire de Parasitologie, École Nationale de Médecine Vétérinaire de Sidi Thabet, Université de la Manouba, 2020, Manouba, Tunisie.
Jacob Lorenzo-MoralesUniversity Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, La Laguna, Tenerife, Canary Islands, Spain.
José E PiñeroUniversity Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, La Laguna, Tenerife, Canary Islands, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the World Health Organization, leishmaniasis is considered as a major neglected tropical disease causing an enormous impact on global public health. Available treatments were complicated due to the high resistance, toxicity, and high cost. Therefore, the search for novel sources of anti-leishmania agents is an urgent need. In the present study, an in vitro evaluation of the leishmanicidal activity of the essential oil of Tunisian chamomile (Matricaria recutita L.) was carried out. Chamomile essential oil exhibits a good activity on promastigotes forms of L. amazonensis and L. infantum with a low inhibitory concentration at 50% (IC

Indexed as

AnimalsAntiprotozoal AgentsChamomileInhibitory Concentration 50LeishmaniaLeishmaniasisMatricariaMembrane Potential, MitochondrialMonocyclic SesquiterpenesOils, VolatileParasitic Sensitivity TestsPhosphatidylserinesPlant ExtractsSesquiterpenesTunisiaAntiprotozoal AgentsbisabololMonocyclic SesquiterpenesOils, VolatilePhosphatidylserinesPlant ExtractsSesquiterpenesApoptosisATP levelsChamomileLeishmaniaMitochondrial membrane potential(−)-α-Bisabolol

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.