Evidence map›Paper›PMID 29955940›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018

A comprehensive review of the clivus: anatomy, embryology, variants, pathology, and surgical approaches.

Rabjot Rai, Joe Iwanaga, Ghaffar Shokouhi, Marios Loukas, Martin M Mortazavi, Rod J Oskouian, R Shane Tubbs

Abstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Image guided endonasal endoscopic approach to different clivus pathologies.International journal of surgery case reports · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Clival and Paraclival Lesions: A Pictorial Review.The Indian journal of radiology & imaging · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Endoscopic Endonasal Approach in Clival Chordoma Surgery: Case Series.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2021
    Article
  19. Anatomical variations of clivus: a descriptive anatomical study.Surgical and radiologic anatomy : SRA · 2021
    Article
  20. Clivus pathologies from diagnosis to surgical multidisciplinary treatment. Review of the literature.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Rabjot RaiDepartment of Anatomical Sciences, St. George's University, St. George's, Grenada.
Joe IwanagaSeattle Science Foundation, 550 17th Ave, James Tower, Suite 600, Seattle, WA, 98122, USA. joei@seattlesciencefoundation.org.
Ghaffar ShokouhiNeurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Marios LoukasDepartment of Anatomical Sciences, St. George's University, St. George's, Grenada.
Martin M MortazaviCalifornia Institute of Neuroscience, Thousand Oakes, CA, USA.
Rod J OskouianSwedish Neuroscience Institute, Seattle, WA, USA.
R Shane TubbsDepartment of Anatomical Sciences, St. George's University, St. George's, Grenada.
St. George's University · GDSwedish Medical Center · USTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe clivus is a bony structure formed by the fusion of the basioccipital and basispheniod bone at the sphenooccipital synchondrosis. This downward sloping structure from the dorsum sellae to the foramen magnum is derived from mesoderm and ectoderm properties.

methodsThis comprehensive review of the clivus will discuss its basic anatomy, embryology, pathological findings, and surgical implications. The clivus is an endochondral bone, formed under two processes; first, a cartilaginous base is developed, and it is secondly reabsorbed and replaced with bone. Knowledge of its embryological structure and growth of development will clarify the pathogenesis of anatomical variants and pathological findings of the clivus.

conclusionsUnderstanding the anatomy including proximity to anatomical structures, adjacent neurovasculature properties, and anatomical variants will aid neurosurgeons in their surgical management when treating pathological findings around the clivus.

Indexed as

Cranial Fossa, PosteriorForamen MagnumHumansNeurosurgical ProceduresOccipital BoneAnatomyClivusEmbryologyNotochordSkull baseSurgery

Identifiers

PMID29955940
OpenAlexW2810229075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.