ArticleAmerican journal of epidemiology2018
A Bayesian Approach to Understanding Sex Differences in Tuberculosis Disease Burden.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Tuberculosis case fatality is higher in male than female patients in Europe: a systematic review and meta-analysis.Infection · 2024Pooled it
- Systematic Review and Meta-Analysis of Sex Differences in Social Contact Patterns and Implications for Tuberculosis Transmission and Control.Emerging infectious diseases · 2020Pooled it
- Assessing the gender responsiveness of tuberculosis interventions: a scoping review (2000-2025).Systematic reviews · 2026Article
- Modelling the impact of increasing tuberculosis treatment coverage and addressing determinants of risk in men.Communications medicine · 2026Article
- A new method to estimate factors associated with tuberculosis transmission using whole genome sequencing and other additional metadata.Epidemiologic methods · 2026Article
- Frequency of tuberculosis symptoms at repeat visits amongst adults attending for HIV care in Gauteng province, South Africa.BMC public health · 2025Article
- Extrapulmonary tuberculosis in The Netherlands, an epidemiologic overview, 1993-2022.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Sex-related absolute inequalities in tuberculosis incidence in 47 countries in Africa.BMC medicine · 2025Article
- Finding the missing men with tuberculosis: a participatory approach to identify priority interventions in Uganda.Health policy and planning · 2025Article
- Article
- Who Transmits Tuberculosis to Whom: A Cross-Sectional Analysis of a Cohort Study in Lima, Peru.American journal of respiratory and critical care medicine · 2024Article
- Preventing tuberculosis with community-based care in an HIV-endemic setting: a modelling analysis.Journal of the International AIDS Society · 2024Article
- Treatment preferences among people at risk of developing tuberculosis: A discrete choice experiment.PLOS global public health · 2024Article
- Preventing tuberculosis with community-based care in an HIV-endemic setting: a modeling analysis.medRxiv : the preprint server for health sciences · 2023Article
- Gender-Specific Association Between Perceived Stigma Toward Tuberculosis and Acceptance of Preventive Treatment Among College Students With Latent Tuberculosis Infection: Cross-Sectional Analysis.JMIR public health and surveillance · 2023Article
- Drivers of sex differences in the South African adult tuberculosis incidence and mortality trends, 1990-2019.Scientific reports · 2023Article
- Influence of Sex and Sex-Based Disparities on Prevalent Tuberculosis, Vietnam, 2017-2018.Emerging infectious diseases · 2023Article
- Tuberculosis Disability Adjusted Life Years, Colombia 2010-2018.Tropical medicine and infectious disease · 2022Article
- Social determinants of the changing tuberculosis prevalence in Việt Nam: Analysis of population-level cross-sectional studies.PLoS medicine · 2022Article
- Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990-2019: results from the Global Burden of Disease Study 2019.The Lancet. Infectious diseases · 2022Article
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5 authors.
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Abstract
Globally, men have a higher epidemiologic burden of tuberculosis (incidence, prevalence, mortality) than women do, possibly due to differences in disease incidence, treatment initiation, self-cure, and/or untreated-tuberculosis mortality rates. Using a simple, sex-stratified compartmental model, we employed a Bayesian approach to explore which factors most likely explain men's higher burden. We applied the model to smear-positive pulmonary tuberculosis in Vietnam (2006-2007) and Malawi (2013-2014). Posterior estimates were consistent with sex-specific prevalence and notifications in both countries. Results supported higher incidence in men and showed that both sexes faced longer durations of untreated disease than estimated by self-reports. Prior untreated disease durations were revised upward 8- to 24-fold, to 2.2 (95% credible interval: 1.7, 2.9) years for men in Vietnam and 2.8 (1.8, 4.1) years for men in Malawi, approximately a year longer than for women in each country. Results imply that substantial sex differences in tuberculosis burden are almost solely attributable to men's disadvantages in disease incidence and untreated disease duration. The latter, for which self-reports provide a poor proxy, implies inadequate coverage of case-finding strategies. These results highlight an urgent need for better understanding of gender-related barriers faced by men and support the systematic targeting of men for screening.
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