ArticleJournal of speech, language, and hearing research : JSLHR2018
Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease.
Article in Journal of speech, language, and hearing research : JSLHR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Speech, voice, and language outcomes following deep brain stimulation: A systematic review.PloS one · 2024Pooled it
- Language skills in Parkinson's disease: state of the art.Dementia & neuropsychologia · 2026Review
- Pauses as a Quantitative Measure of Linguistic Planning Challenges in Parkinson's Disease.Brain sciences · 2025Article
- Speech Acoustic Markers Can Detect Mild Cognitive Impairment in Parkinson's Disease.IEEE journal of selected topics in signal processing · 2025Article
- Influence of Language Dominance on Crosslinguistic and Nonlinguistic Interference Resolution in Bilinguals.Bilingualism (Cambridge, England) · 2025Article
- Variability in Vowel Space in Parkinson's Disease: Associations With Cognitive and Motor Impairment.Journal of speech, language, and hearing research : JSLHR · 2024Article
- Narrative discourse production in Parkinson's disease: Decoupling the role of cognitive-linguistic and motor speech changes.Heliyon · 2023Article
- Reading and lexical-semantic retrieval tasks outperforms single task speech analysis in the screening of mild cognitive impairment and Alzheimer's disease.Scientific reports · 2023Article
- Pausing before verb production is associated with mild cognitive impairment in Parkinson's disease.Frontiers in human neuroscience · 2023Article
- Cognitive profile of patients with and without speech impairment in Parkinson's disease.Dementia & neuropsychologia · 2023Article
- Speech error rates after a sports-related concussion.Frontiers in psychology · 2023Article
- Global Coherence and Cognition in Parkinson's Disease.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Comparing different approaches for operationalizing subjective cognitive decline: impact on syndromic and biomarker profiles.Scientific reports · 2021Article
- Spatio-Semantic Graphs From Picture Description: Applications to Detection of Cognitive Impairment.Frontiers in neurology · 2021Article
- The Impact of Parkinson's Disease on Breath Pauses and Their Relationship to Speech Impairment: A Longitudinal Study.American journal of speech-language pathology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose: Early cognitive symptoms such as word-finding difficulty (WFD) in daily conversation are common in Parkinson's disease (PD), but studies have been limited by a lack of feasible, quantitative measures. Linguistic analysis, focused on pauses in speech, may yield markers of impairment of cognition and communication in PD. The objective of this study was to evaluate the relationship of linguistic markers in semistructured speech to WFD symptoms and cognitive function in PD. Method: Speech recordings of description of the Cookie Theft picture in 53 patients with PD without dementia and 23 elderly controls were analyzed with Praat software. Montreal Cognitive Assessment (MoCA; Nasreddine et al., 2005), category naming fluency, and confrontation naming tests were administered. Questionnaires rating WFD symptoms and cognitive instrumental activities of daily living were completed. We determined the relationships between (a) pause length and location, (b) MoCA score, and (c) WFD symptoms, using Pearson's correlations and multivariate regression models. Results: Compared with controls, patients with PD had more pauses within utterances as well as fewer words per minute and a lower percentage of well-formed sentences. Pauses within utterances differed significantly between PD-mild cognitive impairment and normal cognition (p < .001). Words per minute and percentage of well-formed sentences were predictive of MoCA in multivariate regression models. Pauses before verbs were associated with patient-reported severity of WFD symptoms (p = .006). Conclusions: Linguistic markers including pauses within utterances distinguish patients with PD with mild cognitive symptoms from elderly controls. These markers are associated with global cognitive function before the onset of dementia. Pauses before verbs and grammatical markers may index early cognitive symptoms such as WFD that may interfere with functional communication. Supplemental Material: https://doi.org/10.23641/asha.6615401.
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