Evidence map›Paper›PMID 29955725›Full record

ArticleCurrent developments in nutrition2018

Dietary Uridine Decreases Tumorigenesis in the

Martha S Field, Xu Lan, Denise M Stover, Patrick J Stover

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Martha S FieldDivision of Nutritional Sciences, Cornell University, Ithaca, NY.
Xu LanDivision of Nutritional Sciences, Cornell University, Ithaca, NY.
Denise M StoverDivision of Nutritional Sciences, Cornell University, Ithaca, NY.
Patrick J StoverDivision of Nutritional Sciences, Cornell University, Ithaca, NY.
Cornell University · US

Funding

Homeostatic Regulation of Folate MetabolismR37DK058144 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI STOVER, PATRICK J · 2012 to 2021
$3.7M
NIDDK NIH HHS R37 DK058144
6 · The paper itself

Abstract

backgroundDietary deoxyuridine and uridine have been shown to have opposing effects on neural tube defect (NTD) incidence in the serine hydroxymethyltransferase 1 (

objectiveThis study examined the effects of the dietary pyrimidine nucleosides uridine, thymidine, or deoxyuridine on intestinal tumorigenesis in the

methods

results

conclusionsDietary uridine, which is teratogenic in mice, decreases intestinal tumor formation in the

Indexed as

5-fluorouracilcolon cancerdeoxyuridinefolate-mediated one-carbon metabolismmethotrexatethymidineuridine

Identifiers

PMID29955725
PMCPMC5998365
OpenAlexW2792757133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.