ArticleScientific reports2018
The Open Source GAITOR Suite for Rodent Gait Analysis.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Anti-Inflammatory Treatment and Active Physical Therapy Have Differing Effects on Functional, Mechanical, and Histological Properties in a Rat Model of Post-Traumatic Elbow Contracture.Journal of biomechanical engineering · 2026Article
- Comorbid hypertension and osteoarthritis exacerbates joint remodeling and gait compensations in female rats with milder effects observed in males.Osteoarthritis and cartilage open · 2025Article
- Soft Tissue Injury and Immobilization Are Both Required for Persistent Elbow Contracture in a Rat Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Early resistance rehabilitation improves functional regeneration following segmental bone defect injury.NPJ Regenerative medicine · 2024Article
- Gait assessment in a female rat Sprague Dawley model of disc-associated low back pain.Connective tissue research · 2024Article
- Vagotomy accelerates the onset of symptoms during early disease progression and worsens joint-level pathogenesis in a male rat model of chronic knee osteoarthritis.Osteoarthritis and cartilage open · 2024Article
- The efficacy of vitamin E in preventing arthrofibrosis after joint replacement.Animal models and experimental medicine · 2024Article
- A longitudinal rat model for assessing postoperative recovery and bone healing following tibial osteotomy and plate fixation.BMC musculoskeletal disorders · 2023Article
- Early Resistance Rehabilitation Improves Functional Regeneration Following Segmental Bone Defect Injury.Research square · 2023Article
- Intra-articular delivery of an indoleamine 2,3-dioxygenase galectin-3 fusion protein for osteoarthritis treatment in male Lewis rats.Arthritis research & therapy · 2023Article
- Suppression of local inflammation via galectin-anchored indoleamine 2,3-dioxygenase.Nature biomedical engineering · 2023Article
- High frequency alternating current neurostimulation decreases nocifensive behavior in a disc herniation model of lumbar radiculopathy.Bioelectronic medicine · 2023Article
- Intra-Articular Delivery of an Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein for Osteoarthritis Treatment in Male Lewis Rats.Research square · 2023Article
- Recommendations for the analysis of rodent gait data to evaluate osteoarthritis treatments.Osteoarthritis and cartilage · 2023Review
- African Spiny Mice (Cartilage · 2023Article
- Age alters gait compensations following meniscal injury in male rats.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Assessment of osteoarthritis functional outcomes and intra-articular injection volume in the rat anterior cruciate ligament transection model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Females and males exhibit similar functional, mechanical, and morphological outcomes in a rat model of posttraumatic elbow contracture.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021Article
- Evaluating Gait and Locomotion in Rodents with the CatWalk.Current protocols · 2021Article
- A Low-Cost, Autonomous Gait Detection and Estimation System for Analyzing Gait Impairments in Mice.Journal of healthcare engineering · 2021Article
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Authors and funding
10 authors.
Funding
Abstract
Locomotive changes are often associated with disease or injury, and these changes can be quantified through gait analysis. Gait analysis has been applied to preclinical studies, providing quantitative behavioural assessment with a reasonable clinical analogue. However, available gait analysis technology for small animals is somewhat limited. Furthermore, technological and analytical challenges can limit the effectiveness of preclinical gait analysis. The Gait Analysis Instrumentation and Technology Optimized for Rodents (GAITOR) Suite is designed to increase the accessibility of preclinical gait analysis to researchers, facilitating hardware and software customization for broad applications. Here, the GAITOR Suite's utility is demonstrated in 4 models: a monoiodoacetate (MIA) injection model of joint pain, a sciatic nerve injury model, an elbow joint contracture model, and a spinal cord injury model. The GAITOR Suite identified unique compensatory gait patterns in each model, demonstrating the software's utility for detecting gait changes in rodent models of highly disparate injuries and diseases. Robust gait analysis may improve preclinical model selection, disease sequelae assessment, and evaluation of potential therapeutics. Our group has provided the GAITOR Suite as an open resource to the research community at www.GAITOR.org , aiming to promote and improve the implementation of gait analysis in preclinical rodent models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.