Evidence map›Paper›PMID 29954848›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Chrna5-Expressing Neurons in the Interpeduncular Nucleus Mediate Aversion Primed by Prior Stimulation or Nicotine Exposure.

Glenn Morton, Nailyam Nasirova, Daniel W Sparks, Matthew Brodsky, Sanghavy Sivakumaran, Evelyn K Lambe, Eric E Turner

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 51 citations in OpenAlex.

  1. Disruption ofiScience · 2026
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  10. Extracellular ATP Neurotransmission and Nicotine Sex-Specifically Modulate Habenular Neuronal Activity in Adolescence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
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  11. Article
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  13. Impact of the gut microbiome on nicotine's motivational effects and glial cells in the ventral tegmental area in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Glenn MortonCenter for Integrative Brain Research, Seattle Children's Research Institute.ORCID 0000-0002-4823-3116
Nailyam NasirovaCenter for Integrative Brain Research, Seattle Children's Research Institute.
Daniel W SparksDepartment of Physiology.
Matthew BrodskyCenter for Integrative Brain Research, Seattle Children's Research Institute.
Sanghavy SivakumaranDepartment of Physiology.
Evelyn K LambeDepartment of Physiology.ORCID 0000-0002-5994-6090
Eric E TurnerCenter for Integrative Brain Research, Seattle Children's Research Institute, eric.turner@seattlechildrens.org.ORCID 0000-0001-5499-6788
Czech Academy of Sciences, Institute of Physiology · CZUniversity of Toronto · CAUniversity of Washington · US

Funding

Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI GURALNICK, MICHAEL J · 2014 to 2019
$7.9M
Putting habenula pathways on the mapR01MH093667 · NIMH · SEATTLE CHILDREN'S HOSPITAL · PI TURNER, ERIC E. · 2011 to 2019
$3.6M
Functional studies of the medial habenula in models of reward and mood disordersR01DA035838 · NIDA · SEATTLE CHILDREN'S HOSPITAL · PI TURNER, ERIC E. · 2014 to 2018
$2.1M
NICHD NIH HHS U54 HD083091NIDA NIH HHS R01 DA035838NIMH NIH HHS R01 MH093667NINDS NIH HHS N01 NS002331
6 · The paper itself

Abstract

Genetic studies have shown an association between smoking and variation at the

Indexed as

AnimalsAvoidance LearningCrosses, GeneticExploratory BehaviorFemaleGenes, ReporterInjections, SubcutaneousInterpeduncular NucleusMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicNicotineOptogeneticsPatch-Clamp TechniquesCHRNA5 protein, mouseNicotineReceptors, NicotinicRecombinant Fusion Proteinsacetylcholinechrna5habenulainterpeduncular nucleusnicotineoptogenetics

Identifiers

PMID29954848
PMCPMC6070661
OpenAlexW2811388092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.