ArticleThe Journal of pediatrics2018
Population-Based Validation of a Clinical Prediction Model for Congenital Diaphragmatic Hernias.
Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Clinical characteristics and outcomes of congenital diaphragmatic hernia (CDH) in neonates in an Australian neonatal intensive care unit network: a population-based cohort study.BMJ paediatrics open · 2026Article
- The role of extracorporeal life support and timing of repair in infants with congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- A novel congenital diaphragmatic hernia prediction model for Chinese subjects: A multicenter cohort investigation.Heliyon · 2023Article
- Impact of the COVID-19 pandemic on congenital diaphragmatic hernia patients: a single-center retrospective study.Pediatric surgery international · 2022Article
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- Prenatal stomach position and volume in relation to postnatal outcomes in left-sided congenital diaphragmatic hernia.Prenatal diagnosis · 2022Article
- Genetically Modified Mouse Models of Congenital Diaphragmatic Hernia: Opportunities and Limitations for Studying Altered Lung Development.Frontiers in pediatrics · 2022Review
- Efficacy of Intact Cord Resuscitation Compared to Immediate Cord Clamping on Cardiorespiratory Adaptation at Birth in Infants with Isolated Congenital Diaphragmatic Hernia (CHIC).Children (Basel, Switzerland) · 2021Article
- Perinatal stabilisation of infants born with congenital diaphragmatic hernia: a review of current concepts.Archives of disease in childhood. Fetal and neonatal edition · 2020Review
- Assessment of Antenatal and Postnatal Prognostic Indicators in the Outcome of Neonatal Congenital Diaphragmatic Hernia: A Prospective Observational Study.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo examine the external validity of a well-known congenital diaphragmatic hernia (CDH) clinical prediction model using a population-based cohort. STUDY
designNewborns with CDH born in California between 2007 and 2012 were extracted from the Vital Statistics and Patient Discharge Data Linked Files. The total CDH risk score was calculated according to the Congenital Diaphragmatic Hernia Study Group (CDHSG) model using 5 independent predictors: birth weight, 5-minute Apgar, pulmonary hypertension, major cardiac defects, and chromosomal anomalies. CDHSG model performance on our cohort was validated for discrimination and calibration.
resultsA total of 705 newborns with CDH were extracted from 3 213 822 live births. Newborns with CDH were delivered in 150 different hospitals, whereas only 28 hospitals performed CDH repairs (1-85 repairs per hospital). The observed mortality for low-, intermediate-, and high-risk groups were 7.7%, 34.3%, and 54.7%, and predicted mortality for these groups were 4.0%, 23.2%, and 58.5%. The CDHSG model performed well within our cohort with a c-statistic of 0.741 and good calibration.
conclusionsWe successfully validated the CDHSG prediction model using an external population-based cohort of newborns with CDH in California. This cohort may be used to investigate hospital volume-outcome relationships and guide policy development.
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